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Genome Chemistry and Engineering Lab
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The lab studies plant genomes and develops genome editing technologies.
AboutAbout the lab
Studying genomes to understand and harness them.
The Genome Chemistry and Engineering Lab studies the nuclear and organellar genomes of plants and develops genome engineering technologies such as genome editing.
Using PPR proteins, which are abundant in plants, the lab develops its own DNA and RNA editing technologies and advances their applications.
The lab also investigates how the genomes of chloroplasts, mitochondria, and the nucleus work together to sustain life.
Based on the lab's research results, EditForce, Inc., a Kyushu University startup, was founded in 2015.
Key terms
- PPR protein
- A protein abundant in plants that binds RNA or DNA, made up of a dozen or so repeats of a unit of about 35 amino acids
- Organelle
- A compartment inside a cell. In plants, chloroplasts and mitochondria have their own genomes, separate from the nuclear genome
- Genome editing
- A technology for manipulating specific genes in the genome
NewsLab news
View More ↗ResearchResearch themes
The lab studies the nuclear and organellar genomes of plants and develops genome engineering technologies such as genome editing, and also works on their applied research and practical use. It has two research themes: the development and use of DNA and RNA editing technologies, and research on nucleus-cytoplasm interactions in plants.
*Illustrative imageDevelopment and Use of DNA and RNA Editing Technologies
The lab develops and applies its own DNA and RNA editing technologies based on PPR proteins, which are abundant in plants. In RNA manipulation, it works on understanding and using non-coding RNAs and translation. In DNA manipulation, it works on developing useful crops.
*Illustrative imageNucleus-Cytoplasm Interactions in Plants
In plants, genomes exist in three compartments: the nucleus, mitochondria, and chloroplasts. To understand how they work together to sustain life, the lab uses gene function analysis through organellar genome editing, and studies how to understand and make advanced use of mitochondria-induced pollen sterility (cytoplasmic male sterility).
MembersFaculty
The members of the Genome Chemistry and Engineering Lab consist of faculty, technical staff, technical assistants, administrative assistants, and doctoral, master's, and undergraduate students.
- ProfessorTakahiro Nakamura
- Associate ProfessorTomohiko Kazama
- Project Associate ProfessorMitsuhiro Kimura
- Specific Project Associate ProfessorBernard Gutmann
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Bryophyte Leaf Cells” KarlGaff / CC BY-SA 4.0 (cropped)
- Development and Use of DNA and RNA Editing Technologies: “TIGR-Tas with DNA” Veryspecific / CC0 (cropped)
- Nucleus-Cytoplasm Interactions in Plants: “Allium cepa-cell nucleus” Dr. phil.nat Thomas Geier, Fachgebiet Botanik der Forschungsanstalt Geisenheim. / CC BY-SA 3.0 (cropped)
- Related lab (Marine Biology Lab): “Fish farm Krumë” Arianit / CC BY-SA 4.0 (cropped)
- Related lab (Biochemistry Lab): “LambdaPlaques” No machine-readable author provided. Madboy assumed (based on copyright claims). / CC BY-SA 3.0 (cropped)
- Related lab (Plant Pathology Lab): “Leaves with Rust Infection” Mokkie / CC BY-SA 4.0 (cropped)
- Related lab (Insect Genome Science Lab): “Bombyx mori larvae, Bornholms Sommerfuglepark 21” Ole Palnatoke Andersen / CC BY-SA 3.0 (cropped)
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