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Biomolecular AI Sensing Applications Lab
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A lab that uses nanodevices to distinguish biomolecules one at a time by electrical measurement.
AboutAbout the lab
Measuring single molecules electrically to read biomolecular modifications.
The Biomolecular AI Sensing Applications Lab studies how to identify biomolecules through electrical measurement of single molecules using nanodevices.
The lab has aimed to detect molecular modifications, such as methylation attached to DNA, RNA, and amino acids, at the single-molecule level.
It has also used machine learning techniques to analyze the signals obtained from the measurements.
It is a research field housed in the Institute of Scientific and Industrial Research.
Key terms
- Epiomics
- Research that comprehensively captures molecular modifications and damage on biomolecules in order to understand the effects of disease and environmental change on living organisms
- Single-molecule quantum measurement
- A method that uses a device integrating nanogap channels to measure biomolecules one molecule at a time and distinguish their types and modifications
- MicroRNA
- Small RNAs found inside cells. In this research, they were the focus as targets for distinguishing nucleic acid modifications
ResearchResearch themes
Building on electrical measurement of single molecules with nanodevices, the lab has studied how to detect molecular modifications of biomolecules at the single-molecule level. It has aimed to distinguish modifications of DNA, RNA, amino acids, and peptides, and to use this to understand how disease and environmental change affect living organisms.
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MembersFaculty
- Associate ProfessorTakahito Ohshiro
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “JEOL Electron Beam Lithography (EBL) ( )” Simon Fraser University - Communications & Marketing / CC BY 2.0 (cropped)
- Epiomics by Single-Molecule Quantum Measurement: “DNA molecule closeup” Elapied / Stw (French Wikipedia) / Public domain (cropped)
- Related lab (Materials Biomimetics Lab): “Flexible boards” www.eprlabs.com / CC BY-SA 3.0 (cropped)
- Related lab (Precision Molecular Synthesis Chemistry Lab): “Segment Flow Systems” Jankhughes / CC BY-SA 3.0 (cropped)
- Related lab (Bionanotechnology Lab): “Nanopore-based single molecule mass spectrometry ( )” National Institute of Standards and Technology / Public domain (cropped)
- Related lab (New Industry Creation Systems Lab): “Graphene” Mohammad Javad Kiani, Fauzan Khairi Che Harun, Mohammad Taghi Ahmadi, Meisam Rahmani, Mahdi Saeidmanesh, Moslem Zare / CC BY 2.5 (cropped)
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