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Drug Discovery Informatics Lab
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A lab that uses computers to tackle drug discovery and the mechanisms of disease.
AboutAbout the lab
Tackling drug discovery and disease mechanisms with computers
The Mizuguchi Lab conducts research and technology development that use computers to make drug development more efficient, and works to elucidate the mechanisms of disease.
The lab does not conduct any experiments using animals or microorganisms; its research is carried out entirely with computers.
This field is called bioinformatics, and the lab aims to contribute to drug development in collaboration with researchers who conduct experiments.
On the website, the lab is listed under the name "Mizuguchi Lab" (Computational Biology Lab, Institute for Protein Research).
Key terms
- Bioinformatics
- A field that analyzes data related to living organisms using computers and methods from information science
- Gut microbiota
- The community of various bacteria living in the intestine
- Pharmacokinetics
- The properties describing how a drug changes and moves through the body after it enters
NewsLab news
The lab's paper was published in Cell Reports and also featured in Nature News
The lab's paper was published in ACS Omega
The lab's paper was published in Computational and Structural Biotechnology Journal
A student received the Best Presentation Award at the Institute for Protein Research's graduation research presentation session
The lab's paper was published in Scientific Reports
ResearchResearch themes
The lab combines methods from information science and computational chemistry to elucidate diseases and biological phenomena and to apply the findings to areas such as drug discovery. It focuses on integrating a wide range of data, from molecules centered on genes and proteins to diseases and compounds.
*Illustrative imageData integration linking molecules to biological phenomena
The lab works on data integration to connect molecules with higher-order biological phenomena.
*Illustrative imageAnalysis of the gut microbiota and lifestyle
The lab analyzes associations between the gut microbiota and data such as lifestyle, and also develops platforms for this analysis.
*Illustrative imagePredicting protein interactions
The lab works on understanding and predicting protein-mediated interactions, and on modeling biological reactions.
*Illustrative imagePharmacokinetic prediction for new drug development
The lab works on predicting pharmacokinetics with the aim of creating new drugs.
MembersFaculty
The members of the Mizuguchi Lab consist of faculty members, Project Assistant Professors, technical specialists, technical assistants, secretaries, students in the doctoral program, the master's program, and the undergraduate program, and visiting researchers.As of 2026
- Visiting ProfessorYayoi Natsume
- ProfessorKenji Mizuguchi
- Associate ProfessorKosuke Hashimoto
- Project ProfessorMayumi Kamada
- Project Assistant ProfessorZi Wang
- Project Assistant ProfessorQingwen Chen
VoicesStudent voices
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Flow chart for structure based drug design” Laozhengzz / CC BY-SA 3.0 (cropped)
- Data integration linking molecules to biological phenomena: “Hist1 Biological Network Graph” LuAtOU / CC0 (cropped)
- Analysis of the gut microbiota and lifestyle: “Mixed growth of bacteria-Lactose fermenter (LF) and mucoid LF colonies on MacConkey medium” Ajay Kumar Chaurasiya / CC BY-SA 4.0 (cropped)
- Predicting protein interactions: “LKB1 complex structure 2WTK” Elton Zeqiraj / CC BY-SA 3.0 (cropped)
- Pharmacokinetic prediction for new drug development: “The relationship between Pharmacokinetics and Pharmacodynamics” Claes Lindhardt / CC BY-SA 4.0 (cropped)
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