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Twin Research Center
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A research center that explores the effects of genes and environment through twin studies.
AboutAbout the lab
Exploring the effects of genes and environment with the help of twins.
The Twin Research Center is a center affiliated with the Graduate School of Medicine that builds the foundation for twin research and promotes and supports it.
Twin research is a research method for clarifying the genetic and environmental factors that affect all aspects of human life.
The Center collects DNA, RNA, and serum (blood) samples and questionnaire responses from registered twins, and uses them in joint research with research groups inside and outside the university.
The Center consists of researchers in medicine and health sciences, as well as dentistry, human sciences, economics, pharmaceutical sciences, and other fields.
Key terms
- Genetic and environmental factors
- The parts determined by genes, such as constitution, and the parts shaped by lifestyle habits, educational environment, and the like
- Monozygotic
- Describes twins who are genetically identical at birth
- Omics information
- Comprehensive information on biomolecules. Genomes can be obtained from DNA, and gene expression information from RNA
NewsLab news
A presentation of results from joint research with Shiseido won the Audience Award at the conference of the Japanese Academy of Facial Studies
A student won the Best Presentation Award at the Japan Society for Clinical Laboratory Science Education
ResearchResearch themes
The Twin Research Center aims to clarify how genetic and environmental factors affect human health and behavior through studies of twins. Using samples and questionnaire data from registered twins as a research base, it conducts joint research with researchers inside and outside the university.
*Illustrative imageTwin research across faculties
Researchers in medicine and health sciences, dentistry, human sciences, economics, pharmaceutical sciences, and other fields come together, aiming for interdisciplinary twin research. The research covers human health and behavior.
Collaboration with twin research in Japan
In Japan, twin research participants have been recruited separately by each university, so the number of twin pairs tends to be small, which has been a challenge. The Center is building collaboration with twin researchers in Japan, including through exchanging information on sampling methods.
*Illustrative imageExploring the effects of genes and environment through twins
Monozygotic (identical) twins are genetically identical at birth, but as they live different lives, differences arise in gene expression, and differences in health and behavior appear in middle and older age. Twin research makes it possible to investigate in detail how living environments affect health.
*Illustrative imageCollecting twin samples and questionnaires
With the cooperation of registered twins, the Center collects DNA, RNA, and serum (blood) samples, along with questionnaires on lifestyle habits, educational environment, psychological state, medical history, and more. It analyzes the omics information obtained from the samples together with the questionnaires to carry out advanced analysis of environmental factors.
MembersFaculty
- ProfessorMikio Watanabe
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Twins 2004” Glow at Danish Wikipedia / CC BY-SA 3.0 (cropped)
- Twin research across faculties: “Identical twins lg” National Human Genome Research Institute / Public domain (cropped)
- Exploring the effects of genes and environment through twins: “Indian Twins” Perumalnadar / CC0 (cropped)
- Collecting twin samples and questionnaires: “2026 - Blood test samples” Oleg Yunakov / CC BY-SA 4.0 (cropped)
- Related lab (Cell Recognition Mechanisms Lab): “Fluorescence Microscopy of Mycobacterium tuberculosis Following Auramine O Staining” Siduduziwe Nxumalo / CC BY-SA 4.0 (cropped)
- Related lab (Oncology Lab): “Vacuoles in cancer cells with non-invasive imaging” Annaleida / CC BY-SA 4.0 (cropped)
- Related lab (Molecular Oncology Lab): “Breast cancer cells (2)” Dr. Cecil Fox (Photographer) / Public domain (cropped)
- Related lab (Circulatory Microimaging Medicine Lab): “1982 Prototype of a confocal Laser Scanning Microscope (LSM) ( )” ZEISS Microscopy from Germany / CC BY-SA 2.0 (cropped)
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