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Yamaguchi Lab
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The lab builds metal complexes that mimic the roles of metal ions in living organisms, with the aim of creating artificial proteins.
AboutAbout the lab
Uncovering the roles of metal ions through metal complexes
The lab studies the roles that metal ions play in biological processes by synthesizing metal complexes.
Its research involves designing and synthesizing model complexes of biological metal sites and investigating their biomimetic functions.
The lab aims to deepen understanding of the environments in which metal ions express biological functions, and to create artificial proteins with biomimetic functions.
The Department of Chemistry lists the lab as a concurrent-appointment course of the Center for Education in Liberal Arts and Sciences.
Key terms
- Metal complex
- A compound in which molecules or ions are bound to a metal ion. In this lab, complexes are designed and synthesized as models of biological metal sites.
- Dinuclear metalloenzyme
- An enzyme with two metal centers. It is a subject of research in which the metals or amino acids are replaced to change its function.
- Artificial protein
- A protein created by human design to have functions similar to those of natural proteins. This is the goal the lab is aiming for.
ResearchResearch themes
Living organisms contain various metal ions that play important roles in biological processes. To elucidate their functions, the lab designs and synthesizes model complexes of biological metal sites and studies them.
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MembersFaculty
- ProfessorKazuya Yamaguchi
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Protein Crystal Malic Enzyme” 作者不詳 / Public domain (cropped)
- Biomimetic metal complexes and artificial proteins: “Hemoglobin-3D-model-ribbons” Hoa112008 / Public domain (cropped)
- Related lab (Polymer Reaction Chemistry Lab): “Polypropylene Pellets - DPLA - f7c2fa29d14525ce21219452f4a1a316” Quantum Chemical Corporation / CC BY 4.0 (cropped)
- Related lab (Precision Polymer Science Lab): “Plastic pellets for injection molding” Teemeah / CC BY-SA 3.0 (cropped)
- Related lab (Coordination Chemistry Lab): “Fe(C2O4)(H2O)2-chain-from-xtal-2008-CM-3D-balls” Ben Mills / Public domain (cropped)
- Related lab (Functional Molecular Materials Lab): “Fluorescence of Anthracene under UV light” TimJW12 / CC BY-SA 4.0 (cropped)
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