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Advanced Mass Spectrometry Research Project Lab
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The lab is a research project that opens up new science across fields, centered on the development of mass spectrometers.
AboutAbout the lab
Building instruments that let us see what could not be seen before
The lab develops mass spectrometry instruments and carries out interdisciplinary research using them.
At its core is an instrument called the multi-turn time-of-flight mass spectrometer (MULTUM).
Working closely with researchers in various fields and with industry, the lab aims to develop instruments that “make it possible to see what could not be seen before.”
The lab also works on developing next-generation high-performance mass spectrometers, ionization methods, and detectors, and on nurturing talent.
Key terms
- Multi-turn time-of-flight mass spectrometer
- A mass spectrometer developed by Toyoda and colleagues that achieves high resolution despite its compact size (MULTUM).
- Mass microscope
- A projection-type imaging mass spectrometer that separates and measures masses while preserving the image.
- Geomics
- An effort to comprehensively analyze the atoms and molecules in the environment surrounding the Earth in order to understand the past and present of the global environment.
ResearchResearch themes
Building on the development of innovative mass spectrometers, the lab collaborates with researchers in various fields and with industry to carry out interdisciplinary research, aiming to open up new science. Another goal is to understand the past and present global environment through “geomics,” the comprehensive analysis of atoms and molecules in the environment surrounding the Earth, and to apply this to predicting the near future.
*Illustrative imageMeasuring On Site with Compact Mass Spectrometers
Making use of the multi-turn time-of-flight mass spectrometer developed by Toyoda and colleagues, which achieves high resolution despite its compact size, the lab develops and researches on-site measurement for applications such as medical diagnosis of conditions like periodontal disease, measurement of gases emitted from soil, and planetary exploration.
*Illustrative imageUltra-High-Resolution Mass Microscope
The lab is developing a projection-type imaging mass spectrometer (mass microscope) that ionizes a wide area at once, separates ions by mass with high resolution while preserving the spatial image, and forms that image on a detector. In particular, it is advancing single-cell imaging mass spectrometry technology.
*Illustrative imageUltra-Sensitive Trace-Level Mass Spectrometry
Using a TOF-SIMS instrument that combines a focused ion beam or a femtosecond laser with a multi-turn time-of-flight mass spectrometer, the lab is building methods for measuring isotope ratios.
MembersFaculty
- ProfessorMichisato Toyoda
- Associate ProfessorYoichi Otsuka
- Assistant ProfessorYosuke Kawai
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Thermo - Finnigan LCQ Mass Spectrometer )” Kitmondo Marketplace / CC BY 2.0 (cropped)
- Measuring On Site with Compact Mass Spectrometers: “Liquid chromatograph with a mass spectrometer operating on the principle of flight time in combination with a quadrupole analyzer (qTOF) in CAFIA laboratory, Czech Republic” Sarka Na kopci / CC BY-SA 4.0 (cropped)
- Ultra-High-Resolution Mass Microscope: “Ion Gun” Pani biofizyk / CC BY 4.0 (cropped)
- Ultra-Sensitive Trace-Level Mass Spectrometry: “Focuses Ion Beam 1540 EsB (Zeiss), with EDX and lithography equipment.” Pdubost / CC BY-SA 3.0 (cropped)
- Related lab (Toyoda Lab (Mass Spectrometry Group)): “Secondary Ion Mass Spectrometer (SIMS) Tube - DPLA - 2a22bbd17e faf628d93a557 (page 1)” Honig, Richard E. (Richard Edward) / CC BY 4.0 (cropped)
- Related lab (Challenging Individual Research Division Lab): “Metal-Methylium bonding orbital” Gmvalt / CC BY-SA 4.0 (cropped)
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