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Biomaterials Design Lab
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A medical and healthcare lab that designs and develops biological functions as materials.
AboutAbout the lab
Using the functions of living organisms as materials
The Biomaterials Design Group (Sakai Lab) researches how to use the functions of living organisms as materials, and designs and develops materials and methods that control biological functions.
The lab aims to contribute to medical and healthcare fields such as regenerative medicine, tissue engineering, and drug delivery, as well as to advances in food production.
Its research includes 3D bioprinting, tissue engineering using enzymes, tissue construction using robotics, and Lab-on-a-Chip.
Key terms
- Tissue engineering
- A field that aims to create replacements for tissues and organs with reduced function by combining cells with artificial materials
- 3D bioprinting
- A technology that uses a printer to build tissues and organs by printing them in three dimensions
- Hydrogel
- A jelly-like material. This lab uses materials it synthesizes itself to encapsulate animal cells inside
- Lab-on-a-Chip
- A miniature experimental device built on a chip by microfabrication. Mixing, reaction, separation, detection, and other steps are performed on the chip
NewsLab news
Paper on a hydrogel for injectable DDS (drug delivery system) with reduced immunogenicity risk published in Adv Mater Technol
Presentation on AI × 3D bioprinting wins an Excellence Award at the Society of Chemical Engineers, Japan (SCEJ) Autumn Meeting
Paper published in Biomolecules and selected for the cover
Paper on an analysis of the diversity of the Mediterranean diet accepted by European Journal of Nutrition
Paper on cell-encapsulating 3D bioprinting accepted by ACS Biomaterials Science & Engineering
ResearchResearch themes
The lab designs and develops methods for using the functions of living organisms as materials, along with materials and methods that control biological functions, aiming to contribute to medical and healthcare fields such as regenerative medicine, tissue engineering, and drug delivery. It also works on food production research with the SDGs in mind.
*Illustrative image3D Bioprinting Technology
The lab develops technology to 3D-print replacements for tissues and organs with reduced function. Drawing on knowledge of organic synthesis, it synthesizes ink materials that enhance cell function, and it also designs and builds printers based on an understanding of ink flow.
*Illustrative imageTissue Engineering Using Enzymes
This research uses the ability of enzymes to catalyze reactions even under conditions in which animal cells can survive. The lab develops technology to create substitutes for tissues and organs by encapsulating animal cells in hydrogels it synthesizes itself, and by growing the cells there and retrieving them.
*Illustrative imageRobots That Manipulate and Measure the Cell Environment
The lab develops robotic systems that can manipulate objects around 1 micron in size, for example by grasping and rotating them, and uses them to apply mechanical and chemical stimulation to local regions of cells. Advances in this technology will contribute to establishing methods for building tissues.
*Illustrative imageDevelopment and Applications of Lab-on-a-Chip
Lab-on-a-Chip is a technology that uses microfabrication to make miniature experimental devices with micro- or nanostructures. The lab develops devices that perform mixing, reaction, separation, detection, and other steps on a chip, for applications in chemistry and life sciences.
MembersFaculty
The Biomaterials Design Group consists of faculty members, researchers, doctoral, master's, and undergraduate students, technical assistants, and administrative assistants.As of 2026
- ProfessorShinji Sakai
- LecturerElvitigala Kelum Chamara Manoj Lakmal
- Assistant ProfessorRyota Goto
- Project Assistant ProfessorWildan Mubarok
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Bioprinter project” BEEVERYCREATIVE / CC BY-SA 4.0 (cropped)
- 3D Bioprinting Technology: “Army invests in 3-D bioprinting to treat injured Soldiers” Army Medicine / CC BY 2.0 (cropped)
- Tissue Engineering Using Enzymes: “Superabsorber Hydrogel KSG 2917 pK” Petra Klawikowski / CC BY-SA 3.0 (cropped)
- Robots That Manipulate and Measure the Cell Environment: “PocketDeltaStandalone” User:S.perroud / Public domain (cropped)
- Development and Applications of Lab-on-a-Chip: “Microfluidic chip for point-of-care medical devices” FMNLab / CC BY 4.0 (cropped)
- Related lab (Nano Reaction Engineering Lab): “Liquid Crystal Art-1” Ingo Dierking / CC BY-SA 4.0 (cropped)
- Related lab (Photoenergy and Environmental Chemistry Lab): “Solar energy” Apteva / CC BY-SA 3.0 (cropped)
- Related lab (Surface and Interface Functional Chemistry Lab): “Electrode 2 (PSF)” Pearson Scott Foresman / Public domain (cropped)
- Related lab (Biofunctional Chemistry Lab): “Sugar crystals lie” Star61 / CC BY-SA 4.0 (cropped)
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