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Quantum Beam Applied Engineering Lab
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The lab researches diagnosis and treatment using light and lasers in medicine.
AboutAbout the lab
Shaping the future of medicine with photon beams
The Quantum Beam Applied Engineering Lab (Hazama Lab) researches medicine using photon beams such as lasers and LEDs.
Building on biomedical optics, which theoretically describes how light propagates through biological tissue, the lab works on a broad range of research from basic studies to clinical application.
The lab conducts joint research with physicians, dentists, and medical device manufacturers, aiming to develop medical devices that can actually be used in clinical settings.
Working with the fields of medicine, dentistry, and pharmacy, the lab aims to narrow the gap between average life expectancy and healthy life expectancy.
Key terms
- Biomedical optics
- The field that theoretically describes how light propagates inside biological tissue
- Photodynamic therapy
- A treatment in which light is applied to a drug that accumulates in cancer cells, and the reactive oxygen species generated selectively kill the cancer cells
- Mass spectrometry imaging
- A method that uses mass spectrometry with laser ionization to examine the distribution of drugs and other substances
ResearchResearch themes
In Japan, where the population is rapidly aging and the birthrate is extremely low, the lab focuses on narrowing the gap between average life expectancy and healthy life expectancy, and researches how to apply photon technologies such as lasers and LEDs to medicine. It aims to make it possible to evaluate, through experiments and computer simulations, the efficacy and safety that medical devices need in order to reach practical use.
*Illustrative imageOptical Diagnosis and Treatment of Cancer and Vascular Disease
The lab studies the diagnosis and treatment of cancer and vascular disease based on biomedical optics. It is investigating whether photodynamic diagnosis, which uses fluorescence to detect small tumors, and photodynamic therapy, which selectively kills cancer cells, can be improved.
*Illustrative imageMeasuring Tooth Hardness with Light to Diagnose Cavities
The lab researches techniques that use light to measure tooth hardness, leading to the prevention and early detection of cavities. It is also investigating optical medical devices suited to the early detection and early treatment of cavities and periodontal disease.
*Illustrative imageStudying Drug Pharmacokinetics with Mass Spectrometry
To study how candidate compounds for new drugs behave in the body, the lab researches mass spectrometry imaging using laser ionization. By using atmospheric-pressure ionization with an infrared laser developed in-house, it aims for measurements that are easier and faster than conventional methods.
MembersFaculty
The lab's members consist of faculty, Visiting Professors and Visiting Associate Professors, administrative assistants, and doctoral, master's, and undergraduate students.As of 2026
- Associate ProfessorHisanao Hazama
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Co2-fractional-laser-face-ama-regenerative-medicine” [<a href="https://www.amaskincare.com/about/alice-pien-md-medical-director/">Alice Pien, MD</a>] / CC BY-SA 4.0 (cropped)
- Optical Diagnosis and Treatment of Cancer and Vascular Disease: “Photodynamic therapy 1” Ed Mkh / CC BY-SA 3.0 (cropped)
- Measuring Tooth Hardness with Light to Diagnose Cavities: “LightScalpel Dental CO2 Laser” Academicguru22 / CC BY-SA 4.0 (cropped)
- Studying Drug Pharmacokinetics with Mass Spectrometry: “Biological Mass Spectrometry ( )” Oak Ridge National Laboratory / CC BY 2.0 (cropped)
- Related lab (Quantum Beam Biomaterials Engineering Lab): “Superconducting magnet cutaway 2” Hzofia74 / CC BY 4.0 (cropped)
- Related lab (Quantum Reaction Engineering Lab): “Oak Ridge Spallation Neutron Source Aerial View” ENERGY.GOV / Public domain (cropped)
- Related lab (Laser Applied Engineering Lab [Institute of Laser Engineering]): “Nano-photonics and Optoelectronics Research Laboratory” Mo.moshtaghi / CC BY-SA 4.0 (cropped)
- Related lab (Urban Energy Systems Lab): “Smart grid” Miloš Křivan / CC0 (cropped)
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