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Functional Biomaterials Creation Lab
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A lab that investigates how crystals form inside the body, such as in bone and urinary stones.

AboutAbout the lab
Observe, understand, control.
The Functional Biomaterials Creation Lab studies how crystals that form inside the body (biominerals), such as bone, teeth, and urinary stones, are formed and how they change.
From the perspectives of both crystal engineering and electrical and electronic engineering, the lab makes the behavior of crystals in the body visible using measurement techniques such as optical interferometry.
It is also developing new crystallization techniques using laser light, taking on the challenge of controlling the crystal formation process as desired.
On the lab's website, it is introduced under the name "Maruyama Lab."
Key terms
- Biominerals
- Crystals formed inside living organisms, such as bone, teeth, urinary stones, and vascular calcification, in which inorganic and organic substances are mixed.
- Phase transition
- The phenomenon in which a crystal changes into a different state, such as a stable phase or a metastable phase. Living organisms control this to build bone and teeth.
- Urinary stones (urolithiasis)
- Pathological crystalline tissue that forms due to abnormalities in the body's control mechanisms. Once formed, it is difficult to dissolve, break up, or remove.
NewsLab news
A paper from joint research on predicting the risk of urinary stones was accepted by Scientific Reports
Prof. Maruyama and a master's student won the Annual Meeting Award at the 36th Annual Meeting of the Japanese Society on Urolithiasis Research
ResearchResearch themes
Aiming at the medicine of a future in which people can live long, healthy lives in an aging society, the lab conducts research on biomaterials and biominerals. From the perspectives of both crystal engineering and electrical and electronic engineering, it aims to clarify how crystals in the body form and how they change.
View More ↗MembersFaculty
The members of the Functional Biomaterials Creation Lab consist of faculty, concurrently appointed project faculty, researchers, master's and undergraduate students, technical specialists, and secretaries.As of 2026
- ProfessorMihoko Maruyama
- Assistant ProfessorHozumi Takahashi
- Project Assistant Professor (Concurrent)Yutaro Tanaka
- Project Associate Professor (Concurrent)Eriko Tominaga
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Sugar crystals under a microscope 2” Gustamons / CC0 (cropped)
- Phase transitions of crystals involved in life and their control: “Calcium phosphate crystal” Crop by Mikael Häggström of original by Klinkhardt, Julius ( ) / Public domain (cropped)
- Related lab (Materials Innovation Lab): “Supercontinuum in a microstructured optical fiber” Blinking Spirit, and Dimitris Papadopoulos / CC BY-SA 3.0 (cropped)
- Related lab (Nanomaterial Electronics Lab): “Microchip for Carbon Nanotube Field Effect Transistors fabrication” Aidar Kemelbay / CC BY-SA 4.0 (cropped)
- Related lab (High-Density Matter Reaction Design Lab): “National Ignition Facility's target chamber” Lawrence Livermore National Security / CC BY-SA 3.0 (cropped)
- Related lab (Extreme Plasma Engineering Lab): “The moment a high-power laser pulse interacts with a target to produce a plasma is captured at the Vulcan PW facility ( )” Science and Technology Facilities Council / CC BY-SA 2.0 (cropped)
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