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Higashiyama Lab (Developmental Cell Biology)
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The lab explores how pollen tubes are guided and how organelles divide, using its own original microscopy techniques.
AboutAbout the lab
Finding unknown key molecules with original microscopy techniques
The Developmental Cell Biology Lab studies cell-to-cell communication in plant reproduction, as well as the division of organelles and cells.
The lab is distinguished by its approach: for each phenomenon of interest, it chooses the most suitable biological material and develops its own original techniques.
The lab combines live imaging, synthetic chemistry, and multi-layered omics analysis, among other methods.
Key terms
- Pollen tube
- A thin tube that grows from a pollen grain that has landed on the pistil. It carries sperm cells to the egg cell.
- Organelle
- A small structure within a cell that carries out a specific role, such as mitochondria and chloroplasts.
- Live imaging
- A method of filming living cells or tissues under a microscope and observing how they change over time.
- Non-model organism
- An organism with unique characteristics that is not one of the standard organisms commonly used in research. It is newly established as a research material.
NewsLab news
View More ↗ResearchResearch themes
From phenomena shared widely across living things to highly specialized biological processes, the lab tackles each phenomenon of interest by choosing the most suitable biological material and developing its own original techniques. The main subjects are cell-to-cell communication in plant reproduction and the division of organelles and cells.
*Illustrative imageHow pollen tubes are guided
Inside the flower, plants guide pollen tubes with great precision and quickly form seeds. Using attractant molecules known as "LUREs" as a starting point, the lab follows the process of fertilization with live imaging, aiming to uncover the unknown molecules that act inside the flower and how they function.
*Illustrative imageDivision of mitochondria and chloroplasts
Mitochondria and chloroplasts increase in number only by dividing. Using the primitive red alga Cyanidioschyzon, which has a very simple structure, the lab aims to clarify how organelles and cells proliferate, and to elucidate the function of all the genes of a primitive eukaryote.
*Illustrative imageTechnologies for observing and manipulating cells, and non-model organisms
The lab develops technologies for observing individual cells under the microscope, analyzing molecules, and manipulating them. It has also established non-model organisms with unique characteristics, such as Torenia and Cyanidioschyzon, as experimental materials.
MembersFaculty
The members of the Higashiyama Lab include faculty, secretaries, Academic Specialists, Project Researchers, Visiting Collaborative Researchers, doctoral and master's students, and visiting researchers from overseas.As of 2026
- ProfessorTetsuya HigashiyamaPublications ↗
- Associate ProfessorYamato YoshidaPublications ↗
- Assistant ProfessorYukifumi Uesono
- Assistant ProfessorSatohiro OkudaPublications ↗
- Project Assistant ProfessorYuko Mogi
- Project Assistant ProfessorKumi MatsuuraPublications ↗
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Torenia fournieri2” KENPEI / CC BY-SA 3.0 (cropped)
- How pollen tubes are guided: “Calcium in Pollen” G Lens Microscopist, Nicholas Majkut / CC BY 4.0 (cropped)
- Division of mitochondria and chloroplasts: “Cyanidioschyzon merolae 10D” ja:User:NEON / User:NEON_ja / CC BY-SA 3.0 (cropped)
- Technologies for observing and manipulating cells, and non-model organisms: “Torenia fournieri, Beechview, , 01” Cbaile19 / CC0 (cropped)
- Related lab (Ohsugi Lab): “Mouse blastocyst-microscopy” The original uploader was Enzo at Polish Wikipedia. / CC BY-SA 3.0 (cropped)
- Related lab (Developmental Evolution Lab): “Leaf venation of Dorstenia” SebastianBlumeArt / CC BY-SA 4.0 (cropped)
- Related lab (Plant Physiology Lab): “Marchantia polymorpha - Common Liverwort 03” Jasper Shide / CC0 (cropped)
- Related lab (Genetics Lab (Ohtani Lab)): “Arabidopsis thaliana kz07” Krzysztof Ziarnek, Kenraiz / CC BY-SA 4.0 (cropped)
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