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Developmental Genome Science / Animal Embryology Lab
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A lab that studies the mechanisms of development using ascidians and chickens.
AboutAbout the lab
From a single cell to a whole body
The lab studies the mechanisms of development, using ascidians and chickens as its main experimental organisms.
One line of research uses ascidian embryos to understand how cells differentiate, with the aim of understanding the origin and evolution of chordates. The other uses chicken embryos to explore the basic principles by which vertebrate bodies take shape.
Key terms
- chordates
- A group of animals that have a rod-shaped supporting structure called a notochord along the back. It includes ascidians and vertebrates
- peristalsis
- The wave-like contraction of the gut that moves its contents along
- optogenetics
- A genetic technique that uses light to switch the activity of cells on and off
ResearchResearch themes
The lab studies the mechanisms of development, using ascidians and chickens as its main experimental organisms.
*Illustrative imageCell differentiation in ascidians and the evolution of chordates
The lab aims to understand how cells differentiate during ascidian embryonic development and, through that, the origin and evolution of chordates. Research is mainly experimental, and also includes bioinformatic genome analysis and simple theoretical analysis.
*Illustrative imageGut peristalsis and morphogenesis
Using chicken embryos as a model, the lab treats gut peristalsis as a new morphogenetic signal that guides how organs take shape. Through quantitative analysis of peristalsis and optogenetic manipulation, it investigates how the shape and function of the gut arise.
MembersFaculty
- ProfessorYutaka Sato
- Assistant ProfessorMasafumi Inaba
VoicesStudent voices
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Siphon exhalant d'ascidie (Ciona intestinalis) (Ifremer )” Olivier Dugornay / CC BY 4.0 (cropped)
- Cell differentiation in ascidians and the evolution of chordates: “Ciona savigny” Scott Loarie / CC BY 2.0 (cropped)
- Gut peristalsis and morphogenesis: “Segmentation and Peristalsis” Science Artist / CC0 (cropped)
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