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Particle Beam Medical Physics Lab
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The lab uses physics and engineering to support cancer treatment that targets tumors precisely with neutrons.
AboutAbout the lab
Supporting radiation therapy with physics and engineering
The Particle Beam Medical Physics Lab studies the physics and engineering (medical physics) that support radiation medicine and particle beam medicine.
Its key mission is to advance radiation therapy and ensure its quality (quality assurance).
It focuses in particular on boron neutron capture therapy (BNCT), a type of particle beam therapy, and ultra-high dose rate radiotherapy (FLASH-RT), a next-generation irradiation method.
FLASH-RT is expected to keep the ability to cure tumors while limiting damage to normal tissue.
Key terms
- Boron neutron capture therapy (BNCT)
- A treatment in which a boron drug that accumulates in cancer is administered, and neutrons are then applied to destroy only the cancer cells from the inside
- Quality assurance
- A system for confirming, through regular tests and other checks, that treatment is delivered safely and effectively
- Ultra-high dose rate radiotherapy (FLASH-RT)
- A treatment that delivers radiation at a very high dose rate, in an instant
NewsLab news
A master's student received the Student Presentation Excellence Award at the 69th Symposium on Radiation Chemistry
A master's student received the Poster Excellence Award at the Next-Generation Radiation Symposium 2026
A master's student received the Student Encouragement Award (Bronze) at the 132nd Scientific Meeting of the Japan Society of Medical Physics
A master's student received the Excellent Presentation Award at the 22nd Annual Meeting of the Japanese Society of Neutron Capture Therapy
ResearchResearch themes
To optimize and advance boron neutron capture therapy (BNCT), the lab conducts research on developing neutron irradiation fields, dose evaluation, and quality assurance. It is also working on creating FLASH irradiation fields using an electron accelerator.
*Illustrative imageProducing BNCT neutrons with an accelerator
Together with Sumitomo Heavy Industries, the lab developed an accelerator-based BNCT system (C-BENS) that combines a cyclotron with a beryllium target, and it has been approved as a medical device. The lab continues to develop and improve neutron irradiation fields of various types.
*Illustrative imageDetectors to verify treatment quality
In quality assurance and quality control, which guarantee the effectiveness and safety of treatment, evaluating the dose a patient receives is especially important. The lab is developing real-time neutron and gamma-ray detectors, new scintillator detectors, and more.
*Illustrative imageMeasuring boron concentration in real time
There is still no method to measure in real time how much boron has accumulated in tumors and normal tissue. The lab is developing a telescope system that uses the gamma rays emitted by boron nuclear reactions to measure the boron distribution on the spot.
*Illustrative imageCreating FLASH irradiation fields with electron beams
Using the most intense electron linear accelerator in Japan (KURNS-LINAC), the lab produces ultra-high dose rate electron beams, evaluates the dose with various detectors and simulations, and builds electron FLASH irradiation fields.
MembersFaculty
The members of the Particle Beam Medical Physics Lab consist of faculty, doctoral students, and master's students.
- ProfessorHiroki Tanaka
- Associate ProfessorYoshinori Sakurai
- Assistant ProfessorTakushi Takata
- Program-Specific Assistant ProfessorShangde Hu
- Assistant ProfessorRyo Kakino
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Cyclotron patent” Ernest O. Lawrence / Public domain (cropped)
- Producing BNCT neutrons with an accelerator: “Cyclotron ARRONAX” Popocatomar / CC BY-SA 4.0 (cropped)
- Detectors to verify treatment quality: “Dosimeter measuring radiation in the Chernobyl Exclusion Zone” Jennifer Boyer from Fredrick, Maryland, USA / CC BY 2.0 (cropped)
- Measuring boron concentration in real time: “BNCT Capture Reaction” Ping Mi / CC BY-SA 4.0 (cropped)
- Creating FLASH irradiation fields with electron beams: “SIEMENS Med Museum cyclic and linear electron accelerators” Antonín Ryska / CC BY-SA 4.0 (cropped)
- Related lab (Nuclear Fuel and Materials Engineering Lab): “NTS - Low-level radioactive waste storage pit” Federal Government of the United States / Public domain (cropped)
- Related lab (Particle Beam Materials Engineering Lab): “Later stage of the CLARA Accelerator, Daresbury Laboratory” Mystery Ray / CC0 (cropped)
- Related lab (Neutron Source Engineering Lab): “Núcleo del reactor nuclear RA-3, «Ciencia ficción», by Luis Gauna Pereira” Gaunper / CC BY-SA 4.0 (cropped)
- Related lab (Propulsion Engineering Lab): “Xenon hall thruster” Jet Propulsion Laboratory / Public domain (cropped)
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