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Mathematical Life Sciences Lab
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The lab uncovers the mathematical laws hidden in the shapes of living things.
AboutAbout the lab
Exploring the mathematics hidden in the mechanisms of life
The Mathematical Life Sciences Lab studies the mathematical laws hidden in the mechanisms by which the shapes of living things form in the same way every time.
Its distinguishing feature is that it goes beyond observing organisms, translating their mechanisms into mathematical equations and computer simulation models.
The rules found in living things are also applied to designing robot legs and developing new materials.
The research spans from the movement of molecules to cells, tissues, and organ development, and even to cognitive functions such as "understanding."
Key terms
- Mathematical model
- A representation of how a phenomenon works in mathematical equations, making it possible to predict the phenomenon through calculation
- Chirality
- The property of being, like a right hand and a left hand, a mirror image that looks identical but cannot be superimposed on the original
- Genetic algorithm
- A computational method that imitates biological evolution and gradually selects good solutions
NewsLab news
Joint research with the University of Toyama published in JPSJ
Joint research with Osaka University published in Journal of Cell Biology
Assistant Professor Kentaro Morikawa received an Outstanding Poster Award at the 38th Bioengineering Conference
ResearchResearch themes
The lab works on mathematical life sciences, uncovering the mathematics hidden in the mechanisms of life through mathematical equations and simulation models. It aims to understand everything from matter to the mind in the same mathematical language.
*Illustrative imageHow Are the Shapes of Living Things Determined?
Why do sheets of cells fold, bulge, and form networks? Using mathematical models, the lab showed that asymmetry in the physical environment is one principle that produces different shapes. It also investigates the mechanisms behind beetle horns and the shapes of petals and leaves.
*Illustrative imageReproducing Cells and Tissues on a Computer
The lab developed its own model that represents each cell as a point to simulate the deformation of three-dimensional tissues, and has made the code publicly available. It also compared methods for calculating how easily tissues bend, and clarified how to choose the appropriate method for each purpose.
*Illustrative imageMolecular Handedness and the Cell's Cytoskeleton
Actin filaments, which form the cell's cytoskeleton, build ordered structures simply by aligning so as not to collide with one another. The lab found that when the molecular motor myosin acts, ring-shaped structures rotating in the same direction form spontaneously, and it is exploring the origin of chirality.
*Illustrative imageEngineering Inspired by Living Things
The lab proposed a method that uses a genetic algorithm to design leg mechanisms for walking robots without specifying their shape or motion in advance. It also studies materials that form three-dimensional objects from flat sheets, learning from organisms that vary their growth rate from place to place.
MembersFaculty
The members of the Mathematical Life Sciences Lab consist of faculty, support staff, and doctoral, master's, and undergraduate students.
- ProfessorYasuhiro Inoue
- LecturerMasato Senami
- Assistant ProfessorKentaro Morikawa
VoicesStudent voices
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Shorea robusta leaf pattern” Subhashish Panigrahi / CC BY-SA 4.0 (cropped)
- How Are the Shapes of Living Things Determined?: “Leaf diagram” Kingfiser / CC BY-SA 4.0 (cropped)
- Reproducing Cells and Tissues on a Computer: “3-D Printed Tissue Simulation ( )” The U.S. Food and Drug Administration / Public domain (cropped)
- Molecular Handedness and the Cell's Cytoskeleton: “Chiral molecule example” Calvero. / Public domain (cropped)
- Engineering Inspired by Living Things: “Dew, surface tension 01” Ginanietoc3107 / CC BY-SA 4.0 (cropped)
- Related lab (Quantum Physics Lab): “Client Project Hashcat Testing With an AMD Epyc Supermicro Nvidia GPU Server Using Proxmox (Lawrence Systems) 08” Lawrence Systems / CC BY 3.0 (cropped)
- Related lab (Particle Beam Materials Engineering Lab): “Later stage of the CLARA Accelerator, Daresbury Laboratory” Mystery Ray / CC0 (cropped)
- Related lab (Quantum Beam Science Lab): “Ion Beam - GPN” NASA/GRC / Public domain (cropped)
- Related lab (Quantum Beam Materials Analysis Lab): “High School Student Conducting a X-Ray Diffraction Test” 高柏瑋
（Po-Wei Kao, or Powei Kao） / CC BY-SA 4.0 (cropped)
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