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Environmental Health Lab
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A lab that assesses the risks of environmental pollution from the perspective of health.
AboutAbout the lab
Thinking about the environment from the perspective of health
The Environmental Health Lab studies how chemicals in our surroundings and tiny particles in the air affect human health.
Some environmental pollutants, such as flame retardants, plasticizers, and PM2.5, are a concern for their harmful effects on health and the environment.
The lab investigates how much exposure to a chemical leads to what kind of effect, including the dose-response relationship and the underlying mechanisms.
It aims to establish methods for assessing health risks and to prevent harm to human health before it occurs.
Key terms
- PM2.5
- Very small particles suspended in the air, with a diameter of 2.5 micrometers or less
- Genotoxicity
- The property of chemicals and other agents that damage genes (DNA) and cause mutations or cancer
- Viral vector
- A virus whose pathogenicity has been removed, used in gene therapy to carry a therapeutic gene into the cells of the body
ResearchResearch themes
The lab's main focus is risk assessment of environmental pollutants of concern for their health effects, and elucidation of the mechanisms of those effects. It conducts research that clarifies the relationship between chemical dose and effect, and the mechanisms of action.
*Illustrative imagePreventing Cancer and Infectious Diseases
By measuring markers related to carcinogenesis and analyzing the mutation patterns caused by carcinogens, the lab investigates how environmental pollution contributes to cancer. It is also developing antibodies against new infectious diseases and cancers using its original antibody selection method.
*Illustrative imageMaking Safety Assessment More Reliable
The lab advances genotoxicity tests, which identify carcinogenicity, using cutting-edge mass spectrometry and information technology. It also evaluates the effects that viral vectors used in gene therapy drugs have on organisms in the environment, using cultured cells and molecular biology methods.
*Illustrative imagePredicting the Atmospheric Environment and Assessing Its Effects
Using atmospheric chemical transport models and data science, the lab estimates how much each individual is exposed to air pollutants and applies the results to epidemiological studies. It is also developing deep learning methods to predict pollutant concentrations and solar radiation several hours ahead.
*Illustrative imageEffects of Environmental Pollutants on Immunity
Using cultured cells and animals, the lab investigates the effects of PM2.5, Asian dust, and chemicals in everyday products on respiratory immune diseases, atopic dermatitis, and other conditions, as well as the mechanisms behind them. It is also developing diagnostic technologies that make these effects visible.
MembersFaculty
The members of the Environmental Health Lab consist of faculty, researchers, and doctoral and master's students.
- ProfessorTomonari Matsuda
- Associate ProfessorShun Matsuda
- LecturerKohei Yamamoto
- Assistant ProfessorAkiko Honda
VoicesStudent voices
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Air pollution amid blue skies, the day after reopening from lockdown near Mumbai” Sumaira Abdulali / CC BY-SA 4.0 (cropped)
- Preventing Cancer and Infectious Diseases: “Fluorescence microscopy of the DNA of the oral cancer cells” Korinna / CC BY 4.0 (cropped)
- Making Safety Assessment More Reliable: “Toxicity test ( )” Oak Ridge National Laboratory / CC BY 2.0 (cropped)
- Predicting the Atmospheric Environment and Assessing Its Effects: “Smog in Tokyo” Wilhelm Joys Andersen from Oslo, Norway / CC BY-SA 2.0 (cropped)
- Effects of Environmental Pollutants on Immunity: “Red blood cells (RBCs), platelets and white blood cells or leukocyte (neutrophil) on PBS” Ajay Kumar Chaurasiya / CC BY-SA 4.0 (cropped)
- Related lab (Environmental Risk Engineering Lab): “Soilcontam” Dumelow / CC BY-SA 4.0 (cropped)
- Related lab (Environmental Quality Prediction Lab (Research Center for Environmental Quality Management)): “EPA GULF BREEZE LABORATORY, CHEMISTRY LAB. THE CHEMIST IS TESTING WATER SAMPLES FOR PESTICIDES - NARA - 546277” William C. Shrout / Public domain (cropped)
- Related lab (Geomechanics Lab): “Soil sample Château d’Yquem, Sauternes” Megan Mallen / CC BY 2.0 (cropped)
- Related lab (River Basin Management Engineering Lab): “Bergtocht van S-charl naar Alp Sesvenna. . (d.j.b) 25” Dominicus Johannes Bergsma / CC BY-SA 4.0 (cropped)
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