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Applied Enzymology Lab
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The lab clarifies how enzymes work at the molecular level.
AboutAbout the lab
Exploring how the enzymes that underpin reactions in living organisms work
The Applied Enzymology Lab aims to clarify how enzymes work at the molecular level, from perspectives such as physical chemistry, organic chemistry, and structural biology.
Enzymes are involved in many reactions in living organisms, including the metabolism of food into energy, the synthesis of lipids and hormones, and the replication and expression of genes.
The lab searches for enzymes and proteins involved in the synthesis and metabolism of archaeal membrane lipids, in the synthesis and dynamics regulation of vitamins B6 and B9, and in amino acid metabolism, and investigates their functions.
The lab also pursues applied research such as analysis and material production using enzymes.
Key terms
- Archaea
- The third domain of life, alongside eukaryotes and bacteria. Many archaea can grow in extreme environments
- Enzyme
- A substance involved in the wide range of reactions that take place in living organisms, from the metabolism of food to the replication of genes
NewsLab news
A student received the Amano Enzyme Research Student Award at the 5th Amano Enzyme Research Grant Report Meeting
A master's student received the Young Investigator Excellent Presentation Award at the 98th Annual Meeting of the Japanese Biochemical Society
A master's student received the Student Excellent Presentation Award at the 77th Annual Meeting of the Vitamin Society of Japan
ResearchResearch themes
The lab aims to clarify, at the molecular level, the functions of enzymes involved in a wide range of reactions in living organisms, from perspectives such as physical chemistry, organic chemistry, and structural biology. It also pursues applied research on analysis and material production using enzymes.
*Illustrative imageEnzymes involved in archaeal membrane lipids
The lab searches for enzymes involved in the biosynthesis and metabolism of archaeal isoprenoid compounds, especially membrane lipids, and investigates their functions. It also pursues applied research.
*Illustrative imageMetabolism of vitamins B6 and B9 and amino acids
The lab searches for enzymes and proteins involved in the synthesis and dynamics regulation of vitamins B6 and B9 and in amino acid metabolism, and investigates their functions. It also pursues applied research.
MembersFaculty
The members of the Applied Enzymology Lab are faculty members, technical staff, administrative assistants, and students.As of 2026
- ProfessorHisashi Hemmi
- Associate ProfessorTomokazu Ito
- Assistant ProfessorRyuhei Nagata
VoicesStudent voices
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Isethionate sulfite-lyase crystal structure (with substrate isethionate bound)” Christopher D. Dawson, Lindsey R.F. Backman / CC0 (cropped)
- Enzymes involved in archaeal membrane lipids: “Algae and archaea growing in the runoff of Konungshver” Debivort at en.wikipedia / CC BY-SA 3.0 (cropped)
- Metabolism of vitamins B6 and B9 and amino acids: “B vitamin supplement tablets” Ragesoss / CC BY-SA 3.0 (cropped)
- Related lab (Genome Information Function Lab): “Synechococcus cyanobacteria-cultures” Masur / Public domain (cropped)
- Related lab (Integrative Organic Chemistry Lab): “Laboratory scientist conducts an experiment with a Rotary evaporator” National Eye Institute / CC BY 2.0 (cropped)
- Related lab (Biochemistry Lab): “Arabidopsis thaliana kz08” Krzysztof Ziarnek, Kenraiz / CC BY-SA 4.0 (cropped)
- Related lab (Molecular Cell Regulation Lab): “Calmodulin 1CLL” 作者不詳 / Public domain (cropped)
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