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Obstetrics and Gynecology Lab
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An obstetrics and gynecology department that works on medical care supporting women throughout their lives and on research in areas such as cancer.
AboutAbout the lab
Advancing obstetrics and gynecology care that supports women throughout their lives.
The Obstetrics and Gynecology Lab works on cutting-edge medical care, research, and education to advance obstetrics and gynecology care that supports women throughout their lives.
The recruitment guide introduces what can be done in obstetrics and gynecology, divided into perinatal medicine, reproductive medicine and infertility, endocrinology, and oncology.
The lab's website states that since its founding in 1917, it has played a central role in obstetrics and gynecology care in the Tokai region.
Residents in specialty training and graduate students are part of the lab, and guidance on joining the department and on the graduate school (doctoral program) is also provided.
Key terms
- Exosome
- A vesicle with a lipid bilayer membrane, about 100 nm in diameter, released by all kinds of cells. It is one means of communication between cells
- Peritoneal mesothelial cells
- Cells that cover the surface of the peritoneum. They reduce friction with the intestines and other organs, and are also involved in the healing of wounds inside the abdominal cavity
- Atmospheric pressure plasma
- Plasma used in "plasma medicine," in which plasma is applied to the body to treat disease and injury. Reactive species are thought to act on cells
ResearchResearch themes
The lab's research is presented under four areas: oncology, obstetrics, infertility and reproduction, and clinical trials. In oncology, the lab works on how ovarian cancer spreads to the peritoneum, on exosomes released by cancer cells, and on basic research into plasma-based treatment.
*Illustrative imageSpread of Ovarian Cancer to the Peritoneum
The lab has found that factors from ovarian cancer cells alter peritoneal mesothelial cells, which then draw cancer cells to the peritoneum and increase dissemination. It aims to develop a treatment that suppresses carcinomatous peritonitis by normalizing the peritoneal environment.
*Illustrative imageExosomes Released by Cancer Cells
Focusing mainly on ovarian cancer, the lab studies the role of exosomes released by cancer cells. It has collaborated with the National Cancer Center and aims for applications in diagnosis and treatment.
*Illustrative imageBasic Research on Plasma-Based Treatment of Ovarian Cancer
The lab is exploring a treatment that suppresses intraperitoneal dissemination of ovarian cancer by administering culture medium irradiated with atmospheric pressure plasma into the abdominal cavity. It also studies the mechanism behind the antitumor effects of plasma.
*Illustrative imageChoriocarcinoma and Glycosyltransferases
How a hydatidiform mole progresses through invasive mole to choriocarcinoma is still not understood. The lab focuses on the glycosyltransferases responsible for the hyperglycosylated hCG that increases as trophoblastic cells become malignant.
MembersFaculty
The members of the Obstetrics and Gynecology Lab include faculty, residents in specialty training, PhD students, and international students.As of 2026
- ProfessorHiroaki Kajiyama
- Associate ProfessorTomoko Nakamura
- Associate ProfessorKaoru Niimi
- Associate ProfessorTakafumi Ushida
- LecturerNobuhisa Yoshikawa
- LecturerAkira Yokoi
- LecturerAyako Muraoka
- Hospital LecturerSatoshi Tamauchi
- Hospital LecturerMasato Yoshihara
- Assistant ProfessorNatsuki Miyake
- Assistant ProfessorSho Tano
- Assistant ProfessorReina Sonehara
- Assistant ProfessorYukari Nagao
- Hospital Assistant ProfessorKosuke Yoshida
- Hospital Assistant ProfessorSeiko Matsuo
- Hospital Assistant ProfessorKazuya Fuma
- Project Assistant ProfessorTomomi Seki
- Project Assistant ProfessorShohei Iyoshi
- Hospital Assistant ProfessorYuki Nozaki
- Professor (Medical Administration)Eiko Yamamoto
- Specially Appointed Lecturer (International Collaboration Office)Seiji Sumigama
- Assistant Professor (Center for Genomic Medicine)Kazumasa Mogi
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Scientist checks cell culture flask on microscope” Peter Saxon / CC BY-SA 4.0 (cropped)
- Spread of Ovarian Cancer to the Peritoneum: “Cancer cells (1)” Dr. Cecil Fox (Photographer) / Public domain (cropped)
- Exosomes Released by Cancer Cells: “Sterile 24-Well Cell Culture Plate Used in Laboratory Research” Gannu03 / CC BY-SA 4.0 (cropped)
- Basic Research on Plasma-Based Treatment of Ovarian Cancer: “Atmospheric-pressure plasma” Alibabble / CC0 (cropped)
- Choriocarcinoma and Glycosyltransferases: “Alphafold structure model of pseudonajatoxin b” UniProt database / CC BY 4.0 (cropped)
- Related lab (Gastroenterology Lab): “Medical examination room with ultrasound equipment” Shixart1985 / CC BY 2.0 (cropped)
- Related lab (Diabetes and Endocrinology Lab): “(20250417) Blood glucose meter 09” Roy Zuo / CC BY-SA 4.0 (cropped)
- Related lab (Hematology and Oncology Lab): “FACS-toestel” Biol / Public domain (cropped)
- Related lab (Ophthalmology / Control of Sensory Organ Disorders Lab): “Slit lamp and binocular microscope” OKJaguar / CC BY-SA 4.0 (cropped)
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