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Aoki Lab
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A lab that uses moss to explore the mechanisms and evolution of the biological clock.

AboutAbout the lab
Exploring the evolution of the biological clock through moss
The Aoki Lab conducts research on living organisms, centered on experiments and observation.
Using moss (bryophytes), the lab investigates the mechanism and evolution of the "biological clock" that many organisms have inside their bodies.
The lab invites people who want to study living organisms by seeing and handling them directly, or who want to acquire skills in genetic engineering, to join its research.
Key terms
- Biological clock
- An internal mechanism that many organisms have for autonomously keeping time over the course of a day. Also called the body clock or circadian clock.
- Clock genes
- A group of genes essential for the function of the biological clock. In eukaryotes, they regulate one another to form a network.
- Physcomitrium patens
- A species of moss belonging to the true mosses (Bryopsida). It allows gene targeting, a technique for freely manipulating genes in the genome, to be performed with high efficiency.
NewsLab news
Paper by master's students accepted by Bio-protocol
Paper selected as the cover of Photochemistry and Photobiology
Paper accepted by Biochemical and Biophysical Research Communications
ResearchResearch themes
The Aoki Lab pursues research on living organisms, centered on experiments and observation. Its main work is elucidating the evolution of the biological clock using moss, and studying the mechanisms by which bacteria adapt to their environment.
*Illustrative imageExploring the Evolution of the Biological Clock with Moss
The lab uses the moss Physcomitrium patens to investigate the mechanism and evolution of the biological clock. By comparing the clock gene network with those of higher plants and other organisms, the lab expects to clarify the diversity and origins of the clock.
*Illustrative imageMechanisms of Bacterial Adaptation to the Environment
The lab also conducts research using bacteria such as Escherichia coli and Bacillus subtilis. This is a topic the lab began working on only recently, and it plans to gradually put more effort into it.
MembersFaculty
The members of the Aoki Lab consist of faculty, research students, doctoral and master's students, and undergraduate students.As of 2026
- Associate ProfessorSetsuyuki Aoki
VoicesStudent voices
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Physcomitrella” Pirex at English Wikipedia / Public domain (cropped)
- Exploring the Evolution of the Biological Clock with Moss: “Terramera scientists working in a climate-controlled growth chamber located in Vancouver, BC. The space uses LED lighting, which supports plant growth. ( )” Simon Fraser University - Communications & Marketing / CC BY 2.0 (cropped)
- Mechanisms of Bacterial Adaptation to the Environment: “Coli levine” Witmadrid / Public domain (cropped)
- Related lab (塚本研究室): “Round bottom flask” GOKLuLe / CC BY-SA 3.0 (cropped)
- Related lab (山西研究室
(Yamanishi Lab) ): “Benomyl-3D-molecular-model-engraved-render-CAS” MolGod Scientific / CC BY-SA 4.0 (cropped) - Related lab (太田研究室
(OTA Laboratory) ): “Protein ARF4 (2) PDB 1z6x” Emw / CC BY-SA 3.0 (cropped) - Related lab (時田研究室
(Tokita Laboratory) ): “C.elegans-brain-network” Mentatseb / CC BY-SA 3.0 (cropped)
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