Bioorganic Chemistry Lab (Abe Lab)

AboutAbout the lab

Chemistry-based development of nucleic acid therapeutics

The Abe Lab studies how to design drug molecules and functional molecules, mainly based on nucleic acids.
The lab synthesizes nucleic acid derivatives, which are chemically modified nucleic acids, and develops drug discovery technologies that use them.
A distinctive feature is that everything from building molecules with organic chemistry to confirming how they work with molecular biology can be done in the same lab.
The molecules it creates can also be used in basic life science research and chemical biology research.

ResearchResearch themes

Focusing mainly on nucleic acids, the lab studies design principles for drug discovery molecules and functional molecules from the perspectives of both organic chemistry and molecular biology. It approaches nucleic acid research from two angles: basic and applied.

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Drug Discovery Technologies Using Nucleic Acid Derivatives↗

The lab synthesizes nucleic acid derivatives and develops drug discovery technologies that incorporate them. Keywords include mRNA therapeutics and mRNA vaccines, genome editing therapy, antiviral drugs, anticancer drugs, RNA interference, and antisense nucleic acids.

VoicesStudent voices

Compiled from answers by students who were in the lab. Ratings and reviews reflect individual students' experiences, not the lab's official views.

Students who take part in an interview may receive a thank-you gift worth ¥1,000, regardless of what they say.