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Cellular Information Biophysics (K) Lab
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A biophysics lab that explores proteins and neurons from a physics perspective.

AboutAbout the lab
Exploring how life converts information, from molecules to cells.
The Cellular Information Biophysics Lab (K Lab) studies the mechanisms and processes of information conversion and transmission seen in biological phenomena, using molecules and cells as its subjects.
At the molecular level, the lab works on the mechanism of protein folding and the mechanism that generates circadian rhythms in biological clocks.
At the cellular level, it investigates the mechanism of information transmission at presynaptic nerve terminals and the mechanisms of its plasticity.
In its biological clock research, the lab focuses on the physical aspects of proteins, with the goal of understanding how biological phenomena work.
Key terms
- Folding
- The process by which an unfolded polypeptide chain acquires its specific native three-dimensional structure
- Circadian rhythm
- A periodic behavior with a cycle of about 24 hours
- Synapse
- A structure at the junction between neurons, or between a neuron and a sensory cell or muscle cell
NewsLab news
View More ↗ResearchResearch themes
Biological phenomena involve information conversion and transmission at a wide range of spatial and temporal scales. The lab studies these mechanisms and processes, using molecules and cells as its subjects.
*Illustrative imageMechanism of protein folding
The lab studies folding, the process by which an unfolded polypeptide chain becomes its native three-dimensional structure. Using a variety of spectroscopic methods and rapid kinetic measurements, it examines the intermediates that accumulate along the way in terms of both structure and stability.
*Illustrative imageMolecular mechanism of the cyanobacterial biological clock
The lab investigates how the cyanobacterial clock proteins KaiA, KaiB, and KaiC show circadian rhythms even in a test tube in the presence of ATP. It adds spectroscopic methods to biochemical studies and approaches the question from a physics perspective.
*Illustrative imageInformation transmission and plasticity at presynaptic terminals
Using the frog neuromuscular junction synapse, the lab investigates the exocytosis of synaptic vesicles and the mechanisms of short-term plasticity that regulate the amount of transmitter released. It aims to clarify the roles of divalent cations such as calcium ions through imaging of ion dynamics and electrophysiological measurements.
MembersFaculty
The members of the Cellular Information Biophysics Lab are faculty, master's students, and undergraduate students.As of 2026
- Associate ProfessorKosuke Maki
- Assistant ProfessorNaoya Suzuki
VoicesStudent voices
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Predicted tertiary structure of ZNF568, which is 45.20% identical to the ZNF337 protein sequence. Created using SWISS-MODEL” Saure011 / CC BY-SA 4.0 (cropped)
- Mechanism of protein folding: “Ribbon diagram representation of the folding of the protein barnase” Christopher Rowley / CC BY-SA 4.0 (cropped)
- Molecular mechanism of the cyanobacterial biological clock: “Biological clock human-nn” User:Soulkeeper / CC BY-SA 3.0 (cropped)
- Information transmission and plasticity at presynaptic terminals: “GFP Neurons” ManuelSchottdorf / CC BY-SA 4.0 (cropped)
- Related lab (Photobioenergetics (G) Lab): “Standoff Laser Spectroscopy System ( )” Oak Ridge National Laboratory / CC BY 2.0 (cropped)
- Related lab (Biomolecular Dynamics and Function (D) Lab): “Near-field probing” Clearscience / CC BY-SA 4.0 (cropped)
- Related lab (Nonequilibrium Physics (R) Lab): “LRO granular debris flow on the wall of Stevinus A crater” NASA/GSFC/Arizona State University / Public domain (cropped)
- Related lab (General Relativity and Quantum Cosmology (QG) Lab): “Binary Black Hole” Jeremy Schnittman / CC BY 4.0 (cropped)
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