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Circular Systems Engineering Lab (Keiji Yasuda)
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A lab that creates environmentally friendly chemical processes using ultrasound and tiny bubbles.

AboutAbout the lab
Changing chemistry with sound and bubbles
The Yasuda-Yamaguchi Lab studies high-performance chemical processes with low environmental impact that use ultrasound and fine bubbles (very small bubbles).
The lab also studies properties that are important for chemical process design, such as how liquids and solutions mix and their viscosity.
Liquid properties are investigated from a microscopic, molecular-level perspective through both experiments and computer simulation.
Key terms
- Cavitation
- A phenomenon in which the pressure of a liquid drops, forming small bubbles that then collapse all at once. A field of high temperature and high pressure is created when they collapse.
- Fine bubbles
- Very small bubbles with a diameter of 100 µm or less. They dissolve in water more easily than ordinary bubbles and stay in the liquid longer.
- Molecular simulation
- A method of recreating a collection of molecules inside a computer and investigating their motion and properties through calculation.
NewsLab news
Student's paper published in the Journal of Chemical Physics
Student's paper published in Ultrasonics Sonochemistry
Student wins Excellence Award at the 11th FBU Symposium
Student wins Encouragement Award for Research at the 3rd Fine Bubble Industries Association Academic Awards
Student wins Excellence Award at the 10th FBU Symposium
ResearchResearch themes
The lab develops high-performance chemical processes with low environmental impact using ultrasound and fine bubbles. From a microscopic perspective, it studies properties that are important for chemical process design, such as the phase behavior and viscosity of liquids and solutions, through both experiments and computer simulation.
*Illustrative imageChemical processes driven by ultrasound
When ultrasound is applied to water, tiny bubbles form, and when they collapse they create a field of high temperature and high pressure (cavitation). Using this field, the lab studies producing high-purity gold nanoparticles at room temperature without adding chemicals, and separating valuable substances such as alcohol using ultrasonic mist.
*Illustrative imageProcesses using fine bubbles
Fine bubbles have a large surface area and features such as making gas dissolve easily in water. The lab studies separating and cleaning oil using only air fine bubbles, without flocculants or detergents, and producing ultrafine bubbles quickly with ultrasound.
*Illustrative imageMeasuring the mechanism of liquid viscosity
The lab applies a very rapidly oscillating shear flow to a liquid to measure its viscosity, and examines how long it takes for the liquid structure responsible for viscosity to return to its original state. It has developed an instrument that measures viscosity at high frequencies in the GHz range and uses it on ionic liquids and lithium-ion battery electrolytes.
*Illustrative imageStatistical mechanics theory and molecular simulation
By combining the statistical mechanics theory of liquids with molecular simulation, the lab aims to understand the macroscopic properties of liquids and solutions. It works on developing methods to calculate whether two liquids will mix or separate, and on simulations of charged polymers.
MembersFaculty
The members of the Yasuda-Yamaguchi Lab consist of faculty and doctoral, master's, and undergraduate students.As of 2026
- Associate ProfessorKeiji Yasuda
- Assistant ProfessorTsuyoshi Yamaguchi
VoicesStudent voices
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Glaskolben” -grimbart / CC BY-SA 3.0 (cropped)
- Chemical processes driven by ultrasound: “Transsonic T 310 ultrasound cleaner” W.carter / CC BY-SA 4.0 (cropped)
- Processes using fine bubbles: “Reflection in a soap bubble edit” Brocken Inaglory. The image was edited by user:Alvesgaspar / CC BY-SA 3.0 (cropped)
- Measuring the mechanism of liquid viscosity: “Laboratory equipment of modern chemistry classroom” Belikov Maxim / CC BY 4.0 (cropped)
- Statistical mechanics theory and molecular simulation: “Visual Molecular Dynamics visualization” Toughpkh / Public domain (cropped)
- Related lab (Energy Conversion and Catalytic Materials Engineering Lab): “Solar-hydrogen-panels- -cropped” Jan Rongé / CC BY-SA 4.0 (cropped)
- Related lab (Rate Process Engineering Lab): “Gold and silver nanoparticles in labelled Petri dishes” Drkirstyross / CC BY-SA 4.0 (cropped)
- Related lab (Materials Creation Nanotectonics Engineering Lab): “Nanoart Fluorescence” Яна Сычикова / CC BY 4.0 (cropped)
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