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Organic Structural Chemistry Lab
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The lab synthesizes new π-electron organic molecules and investigates their properties and functions.
AboutAbout the lab
A molecule is only yours once you can synthesize it.
The Shinokubo Lab uses organic synthesis methods to create π-electron organic molecules with shapes and properties never seen before.
No matter how good a molecular design is, the molecule cannot be obtained if it cannot be synthesized. For this reason, the lab places great importance on actually making molecules through a wide range of reactions.
The lab determines the structures of the molecules it makes and investigates their properties and functions in response to light and electricity.
It also aims at applications in electronic materials and medicine.
Key terms
- π electrons
- Electrons that move easily within a molecule when atoms such as carbon form double bonds. They are involved in color and electrical conductivity.
- Antiaromaticity
- A property that appears when a cyclic π-electron system has a number of electrons that is a multiple of 4, making the molecule unstable. It is the counterpart of aromaticity, as seen in benzene.
- Heteroatom
- In an organic molecule, an atom other than carbon and hydrogen, such as nitrogen, sulfur, or oxygen.
NewsLab news
A student received the TCI Poster Award at the 36th Symposium on Basic Organic Chemistry
A paper on chiral non-fullerene semiconductors using figure-eight-shaped molecules was published in Angew. Chem. Int. Ed.
A student received a Poster Award at ISNA-21
A paper on synthesizing chiral nanocarbons by rearranging the framework of figure-eight-shaped molecules was published in Nat. Commun.
Professor Shinokubo received the 78th Chemical Society of Japan Award
ResearchResearch themes
Aiming to open up a new world of molecules through organic synthesis, the lab creates new π-conjugated compounds and investigates their properties and functions. It determines the structures of the molecules it synthesizes and draws out their properties and functions.
*Illustrative imageUnraveling antiaromatic molecules
The lab synthesized the antiaromatic molecule norcorrole, long considered impossible to make, in large quantities, and showed that it can be handled stably in air. It now synthesizes related molecules, studies the properties of antiaromaticity, and works on using them as materials.
*Illustrative imageGiving π-conjugated compounds new properties with heteroatoms
The lab makes compounds in which some of the carbon atoms in the molecular framework are replaced with heteroatoms such as nitrogen and sulfur. Depending on the atoms introduced, properties such as light absorption, electrical conductivity, and light emission differ from those of the original compounds.
*Illustrative imageNew molecules from biological pigments
The lab remodels porphyrin, the framework of heme and chlorophyll, using its own molecular transformation methods, aiming to create molecules with new properties that go beyond their functions in living organisms.
MembersFaculty
The Shinokubo Lab's members consist of faculty, secretaries, and doctoral, master's, and undergraduate students.As of 2026
- ProfessorHiroshi Shinokubo
- Associate ProfessorNorihito Fukui
- Assistant ProfessorHideaki Takano
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Naphthalene-3D-molecular-model-engraved-render-CAS-91-20-3” MolGod Scientific / CC BY-SA 4.0 (cropped)
- Unraveling antiaromatic molecules: “Benzene-3D-molecular-model-engraved-render-CAS-71-43-2” MolGod Scientific / CC BY-SA 4.0 (cropped)
- Giving π-conjugated compounds new properties with heteroatoms: “Heterocyclic nomenclature - assemblies” Mfomich / CC0 (cropped)
- New molecules from biological pigments: “Porphyrin, chlorin, bacteriochlorins” Original work: Livewire61, Expanded derivative work: H Padleckas (talk) / CC BY 3.0 (cropped)
- Related lab (材料設計化学研究グループ): “Lab Mol Colloidal quantum dots 02” Lab mol (Ilia Litvinov) / CC BY 4.0 (cropped)
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（グローバル30 プログラム） ): “RECPIY” Smokefoot / CC BY-SA 4.0 (cropped) - Related lab (多孔材料化学研究グループ): “Zeolite-ZSM-5-3D-vdW” 作者不詳 / Public domain (cropped)
- Related lab (機能物質工学研究グループ): “RLLvsSXTLgraphite” P. Fraundorf / CC BY-SA 3.0 (cropped)
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