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Iwabuchi Lab
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A lab that uncovers the molecular-level battle between plants and pathogens.
AboutAbout the lab
Decoding the molecular-level battle between plants and pathogens.
The Iwabuchi Lab studies the "molecular-level battle" between plants and the pathogens that threaten them, such as filamentous fungi, bacteria, and viruses.
It works to clarify how pathogens hijack plant immunity, and also takes on the development of new industrial technologies that make use of those mechanisms in reverse.
Its goal is to create agricultural technologies for a sustainable future.
The lab's strengths include handling a wide variety of plant pathogenic microorganisms, analyzing microbiomes, and observing gene expression in real time using luminescent reporters.
Key terms
- Filamentous fungi
- Fungi belonging to the mold group. Diseases caused by filamentous fungi account for about 80% of plant diseases, and the spread of strains resistant to chemical pesticides is a challenge
- Effector
- A group of proteins secreted by plant pathogenic bacteria. They play a part in suppressing the plant's immune response and causing morphological abnormalities
- Resistance inducer
- A material that stimulates and activates a plant's innate immunity to increase its resistance to disease. It does not act directly on pathogens
ResearchResearch themes
The lab aims to clarify the molecular-level battle between plants and pathogens and to link it to sustainable agricultural technologies. It conducts research on each type of pathogen, namely filamentous fungi, bacteria and phytoplasmas, and viruses, as well as research on resistance inducers that activate plant immunity.
*Illustrative imageInfection strategies of filamentous fungi and strategies for their control
As the emergence of strains resistant to chemical pesticides makes disease control difficult, the lab analyzes the infection strategies of filamentous fungi and the molecular mechanisms by which they acquire drug resistance, from both molecular and ecological perspectives. It aims for next-generation control systems that reduce the burden on the environment while remaining effective for a long time.
*Illustrative imageHow effectors manipulate plants
The lab investigates how effectors secreted by plant pathogenic bacteria such as phytoplasmas disrupt plants' gene networks. It analyzes the process of infection using model plants such as Arabidopsis thaliana and tobacco.
*Illustrative imageInfection and movement of plant viruses
The lab studies the molecular mechanisms by which plant viruses replicate inside plants and move throughout the whole plant, as well as the battle with the host's immune response. Based on this basic research, it aims to establish sustainable antiviral strategies and technologies that block transmission.
*Illustrative imageDisease control with resistance inducers
The lab analyzes the mechanisms of signal transduction and gene response that resistance inducers trigger inside plants. It aims to build practical, environmentally friendly control systems that are unlikely to give rise to drug-resistant pathogens and place little burden on the environment.
MembersFaculty
- Assistant ProfessorNozomu Iwabuchi
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Bitter rot on a Honeycrisp apple” Jesusistmeinhimmelunderde / CC BY-SA 4.0 (cropped)
- Infection strategies of filamentous fungi and strategies for their control: “Zwiebel Halsfäule-Botrytis aclada-6-DLR-NW-jk” Jochen Kreiselmaier, Pflanzenschutzberater am Dienstleistungszentrum Ländlicher Raum Rheinland-Pfalz, DLR-Rheinpfalz inn Neustadt/Wstr. / CC BY-SA 4.0 (cropped)
- How effectors manipulate plants: “Collmer leaf speck1” Alan Collmer, Cornell University / CC0 (cropped)
- Infection and movement of plant viruses: “Blumenkohl Turnip-mosaic-virus-1-DLR-jk” Jochen Kreiselmaier, Pflanzenschutzberatr am DKR-rheinpfalz in Neustadt/Wstr. / CC BY-SA 4.0 (cropped)
- Disease control with resistance inducers: “Healthy crop of potatoes - geograph.org.uk - 482331” Pauline Eccles / CC BY-SA 2.0 (cropped)
- Related lab (Biomass Resource Chemistry Lab): “Food waste in a blue waste container” Nick Saltmarsh / CC BY 2.0 (cropped)
- Related lab (Nakai Lab): “Air Quality Monitoring Station” Michael Coghlan / CC BY-SA 2.0 (cropped)
- Related lab (Soft Matter Ionics Materials Lab): “Ionic Liquid ( )” National Institute of Standards and Technology / Public domain (cropped)
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