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Kirimura Lab
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The lab uses enzymes and microorganisms as catalysts to produce useful substances.
AboutAbout the lab
Making things with enzymes and microorganisms.
The Kirimura Lab conducts research in applied biological chemistry that uses enzymes and microorganisms as catalysts.
It works on developing reactions with new enzymes and searching for microorganisms that live in harsh environments.
It aims for highly safe "biomanufacturing" that is free of undue burden and waste.
Key terms
- Biocatalysis
- A method of using enzymes or microbial cells as catalysts to drive chemical reactions.
- Stereoselective
- The property of producing only the targeted one among the possible three-dimensional orientations of a molecule.
- Metabolic engineering
- A technology that artificially modifies the flow of chemical reactions inside microorganisms so that they produce more of a target substance.
NewsLab news
View More ↗ResearchResearch themes
The Kirimura Lab conducts research in applied biological chemistry, using enzymes and microorganisms as catalysts to produce useful substances. It aims for highly safe, waste-free "biomanufacturing."
*Illustrative imageStereoselective reactions using enzymes
Using newly discovered enzymes, the lab develops reactions that produce only molecules with a targeted three-dimensional structure.
*Illustrative imageHarnessing microorganisms from extreme environments
The lab searches for microorganisms that live in harsh environments (extremophiles) and studies their application to environmentally friendly biotechnology.
*Illustrative imageImproving the fungus that produces citric acid
The lab studies improving the citric acid-producing filamentous fungus Aspergillus niger through genetic engineering and metabolic engineering.
MembersFaculty
- Kotaro Kirimura
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Aspergillus oryzae (koji)” Forrest O. / CC BY-SA 2.0 (cropped)
- Stereoselective reactions using enzymes: “Jeremy the left-coiling snail on top of a right-coiling snail, Theresa” Angus Davison / CC BY-SA 4.0 (cropped)
- Harnessing microorganisms from extreme environments: “Grand prismatic spring” Jim Peaco, National Park Service / Public domain (cropped)
- Improving the fungus that produces citric acid: “Aspergillus niger 01” 作者不詳 / Public domain (cropped)
- Related lab (Umeno Lab): “Lysozyme Protein Crystal in Hanging-Drop Crystallization” Rohit Sharma / CC BY 4.0 (cropped)
- Related lab (Kobori Lab): “Cutaway of a microfiltration module with hollow fiber membranes at a NEWater plant” Z22 / CC BY-SA 4.0 (cropped)
- Related lab (Homma Lab): “Microcrystalls of nickel” Michał Milczarek / CC BY-SA 4.0 (cropped)
- Related lab (Hanada Lab): “Propane tanks” Tomascastelazo / CC BY-SA 4.0 (cropped)
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