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Umezawa Lab
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A lab that tackles health and medical problems through the behavior of nanoparticles.
AboutAbout the lab
Tracking how nanoparticles behave in the body
The Umezawa Lab studies the design and application of nanomaterials that can be used in biomedicine and pharmaceutical sciences.
It has become clear that the biomolecules that make up the body form nanoscale structures and show new behaviors, and the lab investigates the relationship between these structures and disease or health conditions.
The lab's slogan is "Structure determines function," and it places importance on thinking about both materials and living organisms in terms of structure and function.
The lab uses spectroscopic and computational methods to study changes in the structure of biopolymers.
Key terms
- Extracellular vesicle
- A membrane-bound vesicle nanoparticle released from cells. In this lab, fluorescence is used to track how their movement in the body differs by size.
- Long non-coding RNA
- A relatively long RNA that does not carry information for making proteins. In this lab, machine learning is used to explore its tumor-suppressing functions.
- Spectroscopic methods
- Methods that use the interaction between light and matter to examine the structure and state of molecules.
NewsLab news
A paper on the effects of nanoparticles on the secondary structure of proteins has been published in Environ. Sci.: Process. Impacts
A press release on a technology for visualizing the behavior of microplastics in the body has been issued
A student's research presentation was selected for an Encouragement Award at the results briefing of the Smart Healthcare System research division
A paper by a master's student has been published in Environ. Sci. Adv. and selected as a Hot Article
A paper investigating the toxicity mechanism of microplastics using Drosophila has been published in Environ. Sci. Poll. Res.
ResearchResearch themes
The Umezawa Lab studies the design and application of nanomaterials that can be used in biomedicine and pharmaceutical sciences. It considers both materials and living organisms in terms of structure and function, and uses spectroscopic and computational methods to examine how the structure of molecules changes around nanomaterials.
*Illustrative imageControlling amyloid-β aggregation
The lab studies how to control the aggregation of amyloid-β using nanoparticles, coexisting ions, and solvent molecules.
*Illustrative imageA device for isolating cancer-derived nanoparticles
The lab is developing a device that separates and collects nanoparticles derived from cancer cells, aiming to apply it to disease diagnosis.
*Illustrative imageElucidating the functions of long non-coding RNAs
The lab uses machine learning to explore new functions of long non-coding RNAs involved in tumor suppression.
*Illustrative imageTracking the movement of extracellular vesicles in the body
The lab labels extracellular vesicles with fluorescence and tracks how their movement in the body differs depending on their size.
MembersFaculty
Members of the Umezawa Lab consist of faculty, postdoctoral researchers, and doctoral, master's, and undergraduate students.As of 2026
- Associate ProfessorMasakazu Umezawa
VoicesStudent voices
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “SEM of PLG microparticles and nanoparticles” Ybrudno / CC BY-SA 4.0 (cropped)
- Controlling amyloid-β aggregation: “Amyloid - Nodular Pulmonary Amyloidosis” Y. Rosen, MD / CC BY-SA 2.0 (cropped)
- A device for isolating cancer-derived nanoparticles: “Gold Nanoparticles' aggregation” Nadiia Honcharenko / CC BY 4.0 (cropped)
- Elucidating the functions of long non-coding RNAs: “TRNA-Phe yeast 1ehz” Yikrazuul / CC BY-SA 3.0 (cropped)
- Tracking the movement of extracellular vesicles in the body: “Exosome with hsp70” Guillaume Pelletier / CC BY-SA 4.0 (cropped)
- Related lab (上村研究室): “Cardiac Stem Cell Differentiation” Jweiss20 / CC BY 4.0 (cropped)
- Related lab (松本研究室): “Service robot in Japanese restaurant” Saggittarius A / CC BY-SA 4.0 (cropped)
- Related lab (菊池研究室): “Growing razors 01 inorganic layer growing on biomaterial” Jan Ozimek / CC BY 4.0 (cropped)
- Related lab (世良研究室): “Cytopathology of nonkeratinizing squamous cell carcinoma, original” Ravi Mehrotra, Anurag Gupta, Mamta Singh and Rahela Ibrahim / CC BY 2.0 (cropped)
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