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Saito Lab
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The lab works on the synthesis of interlocked compounds and the development of new reactions.

AboutAbout the lab
Linking molecules and creating new reactions.
The Saito Lab mainly studies supramolecular chemistry and transition-metal catalysis.
The lab has developed a new method for synthesizing interlocked compounds such as rotaxanes and catenanes by making use of the catalytic activity of metal complexes.
The lab develops efficient addition reactions and ring-expansion reactions, many of which are highly atom-economical reactions that produce no unnecessary waste.
With biological, pharmaceutical, and biotechnology fields in view, the lab develops new methodologies from the perspective of organic reaction chemistry.
Key terms
- Interlocked compound
- A compound in which molecules are linked by being entangled with each other, such as rotaxanes and catenanes
- Ring-expansion reaction
- A reaction that makes the ring of a cyclic molecule larger
- Highly atom-economical reaction
- A reaction that produces no unnecessary waste
NewsLab news
Paper by a student published
Paper by a student selected as a Very Important Paper in Chemistry-A European Journal
A student wins an outstanding presentation award at the 86th Kanto Branch Symposium of the Society of Synthetic Organic Chemistry, Japan
Paper by a student selected for a journal cover picture
Paper by a student selected as a Hot Paper
ResearchResearch themes
The Saito Lab mainly studies supramolecular chemistry and transition-metal catalysis. It develops new synthetic methods and reactions, with biological, pharmaceutical, and biotechnology fields also in view.
*Illustrative imageSynthesis of interlocked compounds
The lab has developed a new method for synthesizing interlocked compounds such as rotaxanes and catenanes by making use of the catalytic activity of metal complexes. It also investigates the dynamic behavior of the synthesized compounds.
*Illustrative imageDevelopment of efficient new reactions
The lab develops efficient addition reactions and ring-expansion reactions, which yield useful compounds such as medium-sized ring compounds and organoboron compounds. Many of these reactions are highly atom-economical and produce no unnecessary waste.
*Illustrative imageA cross-disciplinary approach to bio-related fields
With biological, pharmaceutical, and biotechnology fields in view, the lab conducts research from the fundamental perspective of organic reaction chemistry and develops new methodologies.
MembersFaculty
The Saito Lab consists of faculty members, master's students, and undergraduate students.As of 2026
- ProfessorShinichi Saito
- Assistant ProfessorYasushige Kawasaki
VoicesStudent voices
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Kolba 250 ml” Aleksander Sobolewski / CC BY-SA 4.0 (cropped)
- Synthesis of interlocked compounds: “Interlocked II” Dnw / CC BY 3.0 (cropped)
- Development of efficient new reactions: “Copper Cadmium catalyst filter” Wetitpig0 / CC BY-SA 3.0 (cropped)
- A cross-disciplinary approach to bio-related fields: “Pipette (NIH BioArt 408)” Courtesy of NIAID Ryan Kissinger / Public domain (cropped)
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