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Matsumoto Lab
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The lab does process systems engineering, taking in everything from molecules to plants.

AboutAbout the lab
Adapting to a changing world with unchanging principles.
The Matsumoto Lab is a process systems engineering lab that handles everything from molecular-level reactions to plant design.
It places top priority on a deep understanding of the fundamental principles of chemical engineering, such as thermodynamics, molecular informatics, transport phenomena, and reaction engineering.
It applies that foundation within a triple bottom line framework that contributes to three things: People, Planet, and Profit.
The lab works on building sustainable green chemical processes, including nitrogen and carbon cycles, safe and reliable operation, and continuous-flow synthesis.
Key terms
- Process systems engineering
- A field that views a chemical plant as a single system and considers its design, operation, and control
- Deep eutectic solvent
- A liquid formed by mixing two or more substances, whose melting point falls greatly as a result. It is used for gas absorption and other purposes
- Rheology
- A field that deals with how easily materials flow and deform. It describes the properties of thick, viscous liquids
NewsLab news
A paper from the lab was published in J. Environ. Chem. Eng.
A paper from the lab was published in J. Jpn. Pet. Inst.
A paper from the lab was published in Colloids and Surfaces A
A paper from the lab was published in Sep. Purif. Technol.
ResearchResearch themes
The lab views molecular-level reactions, transport phenomena, and process design from a “multiscale” perspective. By establishing methodologies for the analysis and integration of systems, it aims to build truly sustainable “green chemical processes.”
*Illustrative imageSolvent Design with Molecular Information and Machine Learning
Selecting deep eutectic solvents for gas absorption by experiments takes a great deal of time and money. The lab developed a “physics-informed machine learning model” that uses molecular information obtained from quantum chemical calculations, enabling rapid solvent design with predictions whose reasoning can be interpreted.
*Illustrative imageReading How Catalyst Ink Is Mixed
The practical use of PEM fuel cells depends heavily on whether the catalyst layer can be coated uniformly. The lab analyzes the complex mixing behavior specific to catalyst slurries, classifies the state of aggregation in the ink with rheological models, and links it to optimal process conditions.
*Illustrative imageReaction Kinetics Models for NOx Adsorption
The mechanisms by which NOx adsorbs and desorbs on new adsorbents are complex and highly uncertain, which makes industrial process design difficult. The lab fits kinetic models such as the Langmuir-Hinshelwood mechanism to experimental data, building a basis for optimizing conditions and scaling up.
*Illustrative imageManufacturing Processes for Biopharmaceuticals
Manufacturing biopharmaceuticals such as peptides and proteins requires extremely precise control of operations. By combining molecular modeling, process modeling, and advanced process control, the lab is building a framework for design and optimization that reduces trial-and-error experiments.
MembersFaculty
The Matsumoto Lab consists of faculty members, doctoral, master's, and undergraduate students, and exchange students.As of 2026
- ProfessorMatsumoto HideyukiPublications ↗
VoicesStudent voices
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Blue Grass Chemical Agent-Destruction Pilot Plant Control Room Operators ( )” PEO ACWA / CC BY 2.0 (cropped)
- Solvent Design with Molecular Information and Machine Learning: “4-Nitrobenzoic-acid-elpot-3D-vdW” Andreas Klamt / CC BY-SA 3.0 (cropped)
- Reading How Catalyst Ink Is Mixed: “Fuel cell NASA p48600ac” 作者不詳 / Public domain (cropped)
- Reaction Kinetics Models for NOx Adsorption: “G G Allen Steam Plant, scrubber” Murr Rhame / CC BY-SA 3.0 (cropped)
- Manufacturing Processes for Biopharmaceuticals: “Human-insulin-hexamer-3D-ribbons” Benjah-bmm27 / Public domain (cropped)
- Related lab (吉川研究室): “Disc Tube module disc with octagonal membrane cushion” Adrian.barna / CC BY-SA 4.0 (cropped)
- Related lab (原田研究室): “CO2-Wäscher” IUTAe.V. / CC BY-SA 3.0 de (cropped)
- Related lab (関口研究室): “Plasma wheel 2 med DSIR2018” G1MFG / CC BY-SA 3.0 (cropped)
- Related lab (山口・黒木研究室): “Electrolyser, rear” CambridgeBayWeather / CC BY-SA 4.0 (cropped)
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