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Hayamizu Lab
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The lab studies the interface between bio and nano, connecting biology and electronics.
AboutAbout the lab
Bridging biology and electronics
The Hayamizu Lab studies the interface between bio and nano, which connects the world of biology with the world of electronics.
The lab focuses mainly on the phenomenon in which designed peptides self-assemble on two-dimensional materials such as graphene.
Using peptides as scaffolds to functionalize surfaces, the lab builds biosensors that detect odor molecules and biomolecules.
The lab uses atomic force microscopy and Raman spectroscopy to study the structure and electronic state of these interfaces.
Key terms
- peptide
- A molecule made of several amino acids linked together. A shorter version of a protein.
- self-assembly
- The process in which molecules gather on their own to form an ordered structure.
- graphene
- A material in which carbon atoms are arranged in a single sheet, with a thickness of just one atom.
NewsLab news
A student's paper was published in ACS Nano
A student's paper was published in ACS Appl. Mater. Interfaces
ResearchResearch themes
The lab studies the interface that connects the world of biology with the world of electronics. To convert the motion of biomolecules into electronic signals, the lab seeks to understand both the molecular structure and the surface electronic state on two-dimensional materials such as graphene at the same time.
*Illustrative imagePeptide self-assembly
Designed peptides self-assemble on atomically flat surfaces such as graphene and MoS2, forming ordered monolayers. Peptides that mimic the sequence of silk proteins have a stable structure and serve as scaffolds for immobilizing other molecules on the surface.
*Illustrative imageBiosensors
The lab uses the surfaces of two-dimensional materials functionalized with peptides as sensors that capture target substances. By arranging receptor-bearing peptides on a graphene field-effect transistor, the lab selectively detected the odor molecule limonene and its enantiomer.
*Illustrative imageInterface measurement
The lab also develops techniques for measuring and observing the interface between bio and nano. These include using an etching method that combines a laser with electrochemistry to produce monolayers from multilayer MoS2, and investigating how adsorbed organic molecules change the electron density of graphene.
MembersFaculty
- ProfessorYuhei HayamizuPublications ↗
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Graphen” AlexanderAlUS / CC BY-SA 3.0 (cropped)
- Peptide self-assembly: “Mixed monolayer” Seth Darling (CNM, Argonne) and Steven Sibener (University of Chicago) / CC BY-SA 2.0 (cropped)
- Biosensors: “Limonene” Aleksander Sobolewski / CC BY-SA 4.0 (cropped)
- Interface measurement: “Atomic Force Microscopy (AFM) tip attached to a tuning fork” Dinesh.dhankhar / CC BY 4.0 (cropped)
- Related lab (早川研究室): “The Bird of Happiness” Strugalina / CC BY 4.0 (cropped)
- Related lab (片瀬研究室): “Wire for ITER superconducting magnets ( )” Oak Ridge National Laboratory / CC BY 2.0 (cropped)
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