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Kojima Lab
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The lab creates drug-delivery materials and cell scaffolds from polymers.
AboutAbout the lab
Medical polymer materials that function “strongly,” “gently,” and “beautifully.”
The Kojima Lab studies the design and fabrication of medical materials based on polymer chemistry.
The lab makes drug carriers and imaging agents for nanomedicine, and cell scaffold materials for regenerative medicine.
Using dendrimers, which are tree-shaped branched polymers, the lab designs materials whose molecular weight and end-group structures are precisely defined.
The work spans material synthesis and property evaluation through to experiments with cells and animals, and the lab also pursues joint research with medical and pharmaceutical labs.
Key terms
- Dendrimer
- A tree-shaped polymer synthesized by repeatedly branching outward from a central core
- Nanomedicine
- Medicine that uses nanometer-scale materials to diagnose and treat disease
- Stimuli-responsiveness
- A material property in which characteristics change in response to external stimuli such as pH, temperature, or light
NewsLab news
A paper by Professor Kojima and colleagues was published in Polymer Journal
A student received the Outstanding Presentation Award at the Materials Science and Engineering Undergraduate Special Research Project Presentation
A paper by Professor Kojima and colleagues was published in NPG ASIA MATERIALS
A paper by Professor Kojima and colleagues was published in Macromolecular bioscience
The Kojima Lab was launched
ResearchResearch themes
Medical polymer materials underpin advanced medical technologies such as nanomedicine, immunotherapy, and regenerative medicine. The Kojima Lab creates medical polymer materials that function “strongly,” “gently,” and “beautifully,” and aims to build design guidelines for functional biomaterials.
*Illustrative imageDelivery to Immune Cells
Lymph nodes are packed with immune cells, so large particles cannot reach their interior. Using dendrimers a few nanometers in diameter, the lab changes the end-group structure to study how to deliver drugs and nucleic acids to T cells.
*Illustrative imageNanoparticles That Accumulate in Tumors
The lab synthesized dendrimers conjugated with polyethylene glycol (PEG) and showed that how water is bound to them is related to how readily they accumulate in tumors. It is confirming this by varying the chain length and the number of attached chains.
*Illustrative imageStimuli-Responsive Materials
Introducing ionic or hydrophobic groups at the ends of dendrimers produces materials that respond to pH and temperature. Loading them with gold nanoparticles makes them respond to light as well, so they can be used for imaging and photothermal therapy.
*Illustrative imageCreating Artificial Proteins
Proteins denature and stop functioning depending on pH, temperature, and solvent. By attaching peptides or amino acids to the ends of dendrimers, the lab is making materials that resemble collagen and elastin but do not denature.
MembersFaculty
The Kojima Lab consists of faculty members and doctoral, master's, and undergraduate students.As of 2026
- ProfessorChie KojimaPublications ↗
- Assistant ProfessorFulati AilifeirePublications ↗
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Cylindrical squalenoyl-doxorubicin nanoparticle” Yesint / CC BY 4.0 (cropped)
- Delivery to Immune Cells: “T Regulatory Cells ( )” NIAID / CC BY 2.0 (cropped)
- Nanoparticles That Accumulate in Tumors: “Nanoparticles ( )” National Institute of Standards and Technology / Public domain (cropped)
- Stimuli-Responsive Materials: “Gold nanoparticles as indicators” Valeg96 / CC BY-SA 4.0 (cropped)
- Creating Artificial Proteins: “Scanning electron microscopy of collagen fibers” NIH Image Gallery / CC BY-SA 4.0 (cropped)
- Related lab (生駒・安楽研究室): “SK8-18-2 human derived cells, fluorescence microscopy ( )” ZEISS Microscopy from Germany / CC BY 2.0 (cropped)
- Related lab (曽根・チャン研究室): “Copper Electroplating Timecourse” Richard Wheeler (Zephyris) / CC BY-SA 3.0 (cropped)
- Related lab (道信研究室): “1inchpolymersolarcell” Aromaticmoleculessmell / CC BY 3.0 (cropped)
- Related lab (矢野研究室): “Refractive Index of Different Glass Samples at Corning Museum of Glass” Henrysz / CC BY 4.0 (cropped)
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