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Yanaka Lab
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The lab decodes the hidden functions of biomolecules and creates new ones.
AboutAbout the lab
Elucidating and creating functions based on biomolecular science
The Yanaka Lab studies the functions of biopolymers such as nucleic acids, proteins, glycans, and lipids.
Deciphering the operating principles of functions hidden within biomolecules advances the understanding of life and disease.
Combining experimental and theoretical approaches, the lab works both to elucidate functions and to create new ones.
Biomolecules, and versions with modified functions, can be put to use in medicine and industry.
Key terms
- Biopolymers
- Large molecules that make up living organisms, such as nucleic acids, proteins, glycans, and lipids
- Antibodies
- A protein that recognizes and binds foreign substances entering the body and triggers immune responses
- Biopharmaceuticals
- Drugs that use proteins and other substances produced by living organisms; antibody-based drugs are a leading example
NewsLab news
Press release on research on an antibody that binds strongly to norovirus
Paper elucidating the structure of the antibody Fc region by NMR published in JACS
Paper visualizing methionine oxidation in antibody drugs published in Anal. Chem.
Paper elucidating the function of the antibody hinge region published in J. Med. Chem.
Paper elucidating how glycans control antibody dynamics published in PNAS
ResearchResearch themes
The lab deciphers the operating principles of functions hidden within biomolecules, contributing to the understanding of life and disease. Combining experiment and theory, it works to elucidate functions and to create new ones.
*Illustrative imageCreating Next-Generation Antibodies
Antibodies have been thought to drive the immune system through a region that recognizes foreign substances and a region that activates immunity. In this lab, new functional sites are being discovered one after another, and the lab is pursuing drug discovery research that makes use of their molecular mechanisms.
*Illustrative imageDesigning Biopharmaceuticals with Information Science
Antibodies are a leading class of biopharmaceuticals, and information science has become an indispensable tool in their design. The lab collects high-quality experimental data on antibody properties and develops new methods that make it possible to design drugs in silico.
MembersFaculty
The members of the Yanaka Lab consist of faculty, administrative support staff, and students in the doctoral, master's, and undergraduate programs.As of 2026
- Associate ProfessorSaeko YanakaPublications ↗
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Protein crystals grown in space” Credits: NASA Marshall Space Flight Center (NASA-MSFC) / Public domain (cropped)
- Creating Next-Generation Antibodies: “Antibody IgG1 structure” Tokenzero / CC BY-SA 4.0 (cropped)
- Designing Biopharmaceuticals with Information Science: “Kraken Supercomputer ( )” Oak Ridge National Laboratory / CC BY 2.0 (cropped)
- Related lab (阿部研究室): “BiodegradablePlasticUtensils1” Scott Bauer / Public domain (cropped)
- Related lab (松下
（伸） ・久保田研究室): “Photoresist spin-coaters at LAAS 0448” Guillaume Paumier (user:guillom) / CC BY-SA 3.0 (cropped) - Related lab (矢野研究室): “Refractive Index of Different Glass Samples at Corning Museum of Glass” Henrysz / CC BY 4.0 (cropped)
- Related lab (三宮研究室): “Gold Colloid of varying size” Kumarbarc / CC BY-SA 4.0 (cropped)
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