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Nishino Lab
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A lab that sandwiches a single molecule between electrodes to explore its properties and put them to use.
AboutAbout the lab
Creating single-molecule chemistry to help solve energy problems.
The Nishino Lab studies the properties and functions of single molecules, each one sandwiched between metal electrodes.
A single molecule held between electrodes can show a wide range of properties. For example, a molecule that normally does not conduct electricity can begin to carry current.
Taking advantage of these properties, the lab is working on elucidating energy conversion mechanisms, single-molecule devices, highly sensitive biosensors, and methods for observing single molecules.
The lab's ultimate goal is to create a new field of chemistry based on single molecules.
Key terms
- Single-molecule junction
- A structure in which a single molecule bridges the gap between two metal electrodes
- Thermoelectric conversion
- The direct conversion of heat energy into electrical energy
- Raman spectroscopy
- A method that shines light on a sample and examines molecular vibrations and bonding from the slight change in color (wavelength) of the scattered light
NewsLab news
Research results accepted for publication in J. Mater. Chem. C
Research results accepted for publication in Small
Research results accepted for publication in Phys. Chem. Chem. Phys.
Research results accepted for publication in ACS Omega
Research results accepted for publication in ACS Appl. Nano Mater.
ResearchResearch themes
The lab aims to clarify the diverse properties and functions of single molecules held between metal electrodes, and to put them to free use. Its work covers measuring energy conversion with single molecules, low-power single-molecule devices, highly sensitive biosensors, and pioneering spectroscopic methods for observing single molecules.
*Illustrative imageSingle-Molecule Measurement of Energy Conversion
The lab is developing a measurement method that captures, at the single-molecule level, light-induced charge separation, the most important step in power generation by solar cells. It also measures thermoelectric conversion, the conversion of heat into electricity, at the single-molecule level.
*Illustrative imageElectronic Components Made from Single Molecules
The lab aims to give a single molecule the function of a device, in pursuit of the smallest possible devices with extremely low power consumption. So far, it has successfully developed single-molecule switches and diodes.
*Illustrative imageBiosensors That Detect Single Molecules
By applying molecular recognition chemistry to single-molecule junctions, the lab is developing methods to select and directly measure just one biomolecule. It has developed a single-molecule detection method for DNA that can also distinguish DNA mutations and damage.
*Illustrative imageSpectroscopy for Observing Single Molecules
The lab is pioneering spectroscopic methods for observing a single molecule sandwiched between electrodes. Using the effect by which light is intensified in the gap between metals, it captured the signal from just one molecule by single-molecule Raman spectroscopy.
MembersFaculty
The members of the Nishino Lab are faculty, administrative assistants, and doctoral, master's, and undergraduate students.As of 2026
- Associate ProfessorTomoaki NishinoPublications ↗
- Project Associate ProfessorShintaro FujiiPublications ↗
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Molecular Electronics ( )” National Institute of Standards and Technology / Public domain (cropped)
- Single-Molecule Measurement of Energy Conversion: “Close-up of a polycrystalline solar PV panel” Guilhem Vellut / CC BY 2.0 (cropped)
- Electronic Components Made from Single Molecules: “ULN2003 Darlington Transistor Array Micrograph” Zeptobars.ru / CC BY 3.0 (cropped)
- Biosensors That Detect Single Molecules: “DNA Helix CPK” Ude / Public domain (cropped)
- Spectroscopy for Observing Single Molecules: “Raman measurement of ionic liquid droplet” Tavo Romann / CC BY 4.0 (cropped)
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