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Pathophysiology Analysis Lab
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The lab aims to understand the pathology of schizophrenia and eating disorders and to support treatment and social reintegration.

AboutAbout the lab
Understanding mental illness from every angle
The lab studies the pathology and treatment of psychiatric disorders, focusing on schizophrenia and eating disorders.
Its main themes are understanding pathology, pursuing treatments, and supporting social reintegration.
Beyond basic research and studies of genes and brain imaging, the lab also pays attention to the individuality of each patient and to their psychological problems.
It works with institutions such as the Department of Psychiatry at Chiba University and carries out many joint studies.
Key terms
- Treatment-Resistant Schizophrenia
- Schizophrenia in which symptoms do not improve sufficiently even with continued standard treatment with antipsychotic drugs.
- Transcranial Magnetic Stimulation
- A method of stimulating part of the brain with a magnetic field applied from outside the head. It is used to study brain function.
- Resting-State fMRI
- A method of using MRI to measure brain activity while a person rests and does nothing, based on changes in blood flow.
NewsLab news
Joint research by Project Assistant Professor Sudo and colleagues clarifies the brain function changes produced by cognitive behavioral therapy for bulimia nervosa
Professor Kanahara's paper published online in Current Neuropharmacology
Professor Kanahara's paper published online in Journal of Psychiatric Research
Professor Kanahara's paper published online in Journal of Neural Transmission
ResearchResearch themes
The lab focuses on schizophrenia and eating disorders, investigating how symptoms arise and what changes with treatment. It combines several methods, including brain imaging, genetics, cognitive function tests, and transcranial magnetic stimulation.
*Illustrative imageSchizophrenia and Clinical Pharmacology
Focusing on treatment-resistant schizophrenia, the lab investigates the pathology of difficult-to-treat symptoms such as cognitive impairment and autistic symptoms. It also puts effort into research on drug therapy, such as dopamine supersensitivity psychosis and responsiveness to clozapine.
*Illustrative imageBrain Function and Treatment in Eating Disorders
Using methods such as resting-state fMRI, the lab investigates what abnormalities exist in brain function in anorexia nervosa and bulimia nervosa, and how the brain changes when symptoms improve with treatment. It conducts joint research with institutions inside and outside the university.
MembersFaculty
The lab's members consist of faculty and doctoral students.As of 2026
- ProfessorNobuhisa Kanahara
- Project Assistant ProfessorYusuke Sudo
- Project Assistant ProfessorYuko Fujita
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “MRI Scan General Illustration” Ptrump16 / CC BY-SA 4.0 (cropped)
- Schizophrenia and Clinical Pharmacology: “Psychiatric Items” Anton / CC BY-SA 4.0 (cropped)
- Brain Function and Treatment in Eating Disorders: “FMRI coronal scan of Nathanial Bradford” Nathanial Luceus / CC BY 2.0 (cropped)
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