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Organic Reaction Chemistry Lab
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The lab makes skillful use of halogens to create environmentally friendly reactions.

AboutAbout the lab
Creating gentle reactions with the power of halogens.
The Organic Reaction Chemistry Lab works on developing reactions that are environmentally benign.
The lab develops new methods of molecular transformation that make skillful use of halogen elements such as iodine and bromine.
It also takes on the design of catalysts made only of organic molecules, which drive reactions without metals.
The lab aims to realize in the flask the precise organic reactions that take place inside living organisms.
Key terms
- Hypervalent iodine
- A compound of iodine in a state with more bonds than usual. It can be used as an oxidant in place of heavy metals
- Organocatalyst
- A catalyst made only of organic molecules, containing no metal
- Halogen bond
- A force by which a halogen atom such as iodine or bromine attracts another molecule and binds to it
NewsLab news
A paper from the lab was published in Organic Letters
A master's student received the Chemistry Letters Young Researcher Award at the 27th Symposium of the Society of Iodine Science
A paper from the lab was published in Advanced Synthesis & Catalysis
A paper from the lab was published in Advanced Synthesis & Catalysis
A paper from the lab was published in Advanced Synthesis & Catalysis
ResearchResearch themes
As reaction development oriented toward environmental harmony, the lab works on developing molecular transformation methods that make skillful use of halogen elements. It also studies the design of organic molecules that act as catalysts.
*Illustrative imageOxidation with Halide Ions
Halide ions are abundant on Earth as salts of alkali metals and other elements, and they are nontoxic and stable. By oxidizing these salts, the lab has realized a number of molecular transformation methods that can replace organic halogenating agents and heavy metals, and has recently extended them to sequential molecular transformations.
*Illustrative imageHypervalent Iodine with Amine–Iodine Bonds
Most conventional hypervalent iodine compounds have oxygen–iodine bonds. Focusing on nitrogen–iodine bonds, the lab has synthesized new compounds with amine–iodine bonds and has realized reactions that directly introduce amino groups, as well as intramolecular cyclization reactions that activate carbon–hydrogen bonds.
*Illustrative imageCreating New Organocatalysts
Organocatalysts attract attention as environmentally friendly catalysts, but their weakness is that their scope is narrower than that of metal catalysts. Taking advantage of the structural flexibility of organic molecules and networks of weak interactions, the lab develops powerful carboxylic acid catalysts and peptide catalysts that use intramolecular hydrogen bonds.
*Illustrative imageIodine-Containing Amino Acids and Peptides
Iodine forms strong halogen bonds and interacts with Lewis bases. The lab makes iodine-containing amino acids that incorporate this property, assembles from them peptides that serve as medium-sized organic molecular materials, and aims to extend the work to pharmaceuticals and organic materials.
MembersFaculty
The members of the Organic Reaction Chemistry Lab consist of faculty and students in the master's program and the undergraduate program.As of 2026
- Associate ProfessorKatsuhiko Moriyama
VoicesStudent voices
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Iodine crystal” 2x910 / CC BY-SA 4.0 (cropped)
- Oxidation with Halide Ions: “Potassium-iodide-3D-ionic” Benjah-bmm27 / Public domain (cropped)
- Hypervalent Iodine with Amine–Iodine Bonds: “Large Iodine crystals” BunGee / CC BY-SA 4.0 (cropped)
- Creating New Organocatalysts: “Formic acid dimer 3D spacefill” Jynto (talk) / CC0 (cropped)
- Iodine-Containing Amino Acids and Peptides: “Alpha endorphin stick molecular model” Mplanine / CC BY-SA 4.0 (cropped)
- Related lab (有機合成化学研究室): “Rampe à vide” Serge Brière / Public domain (cropped)
- Related lab (有機分子化学研究室): “Palladium (46 Pd)” Hi-Res Images of Chemical Elements / CC BY 3.0 (cropped)
- Related lab (環境分析化学研究室): “Nacreous aragonite ("mother-of-pearl") 9” James St. John / CC BY 2.0 (cropped)
- Related lab (生体高分子化学研究室): “Sample of White-Tailed Deer Sperm Under Fluorescent Microscopy” Theprevetvikng / CC BY 4.0 (cropped)
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