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Hayashi-Nagano Lab
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A lab that develops and analyzes medical technologies for less invasive surgical treatment.

AboutAbout the lab
Biomedical engineering that contributes to today's healthcare.
The Hayashi-Nagano Lab develops and analyzes medical technologies for less invasive surgical treatment.
The lab's slogan is "biomedical engineering that contributes to today's healthcare."
Every study is characterized either by validation experiments using living animals, from small to large species, or by analyses based on clinical data and specimens.
The lab also conducts joint research with departments of Chiba University Hospital, such as the pathology and operating room departments.
Key terms
- Liposome
- A small sac made of phospholipids, used to enclose a drug and carry it to a target site in the body.
- Laparoscopic surgery
- Surgery performed by making small incisions in the abdomen and inserting a thin camera and instruments.
- Drug delivery system
- A mechanism or technology for efficiently delivering a drug to the place in the body where it is needed.
ResearchResearch themes
The lab works on technologies for less invasive surgical treatment from both the development and the analysis sides. Its research is characterized by validation experiments using living animals and by analyses based on clinical data and specimens.
*Illustrative imageNear-Infrared Light-Responsive Liposomes and Cancer Immunotherapy
Liposomes containing a near-infrared fluorescent dye are known to generate heat and reactive oxygen species when irradiated with near-infrared light. The lab is developing drug delivery systems that can deliver immunotherapy to cancer-metastasized lymph nodes, for example by encapsulating immune-activating substances.
*Illustrative imageInvestigating Bacterial Contamination in Hospital Laboratories
In cooperation with Chiba University Hospital, the lab collects bacteria in actual hospital laboratories, determines bacterial counts and species, and analyzes the contamination status using the statistical software R. It also conducts clinical research on antibacterial finishing technologies, evaluating how effectively they suppress the transmission of bacteria.
*Illustrative imageSurgical Navigation for Laparoscopic Liver Resection
In laparoscopic liver resection, the surgical field is limited, so support for accurately grasping the positional relationships of tissues is considered necessary. The lab is investigating AR navigation that performs registration using a dual-imaging marker, developed in the lab, that can be detected with high sensitivity under both near-infrared light and X-rays.
*Illustrative imageMedical Data Analysis Using AI
Using actual clinical data provided by Chiba University Hospital and other institutions, the lab builds predictive models for treatment outcomes and cancer metastasis. It also conducts research aimed at diagnostic support, using medical images such as pathology images obtained in clinical practice.
MembersFaculty
The Hayashi-Nagano Lab consists of faculty members and master's and undergraduate students.As of 2025
- Project ProfessorHideki Hayashi
- Assistant ProfessorNahoko Nagano
VoicesStudent voices
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “WBAMC first in DoD to use robot for surgery 160426-A-EK666-506” Marcy Sanchez / Public domain (cropped)
- Near-Infrared Light-Responsive Liposomes and Cancer Immunotherapy: “Liposome Structure” Mlicuana / Public domain (cropped)
- Investigating Bacterial Contamination in Hospital Laboratories: “Bacteria on agar plate” HansN. / CC BY-SA 3.0 (cropped)
- Surgical Navigation for Laparoscopic Liver Resection: “Laparoscopic operating theatre” Dr.jayesh amin / CC BY-SA 3.0 (cropped)
- Medical Data Analysis Using AI: “US Navy 030822-N-9593R-031 The work station area of the Medical Library” U.S. Navy photo by Chief Warrant Officer 4 Seth Rossman. / Public domain (cropped)
- Related lab (医用生体電磁気学研究室
(齊藤研究室) ): “Metallic lens antenna Bell Labs 1946” 作者不詳 / Public domain (cropped) - Related lab (折田研究室): “Projectional radiograph of cervical foraminal stenosis” Mikael Häggström / CC0 (cropped)
- Related lab (生体イメージング研究室
(菅研究室) ): “An MRI scanner” Walter Davies / CC BY-SA 4.0 (cropped) - Related lab (高橋研究室): “Microwave Antenna ( )” Faisal Akram from Dhaka, Bangladesh / CC BY-SA 2.0 (cropped)
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