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Micro-CT and Medical Imaging Engineering Lab
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A lab that images fine 3D structures inside tissue using X-rays and light.
AboutAbout the lab
Measuring internal structure without cutting
This lab studies technologies that visualize and quantify the fine 3D structure of biological tissue, based on micro X-ray CT systems and optical coherence tomography (OCT).
The lab develops technology on both the hardware and software sides, from building imaging systems to image reconstruction, image quality improvement, and 3D image analysis.
In OCT, the lab collaborates with the ophthalmology department of a university hospital and quantifies structural changes in the retina and choroid of diseased eyes.
The lab aims not to stop at viewing images, but to turn them into quantitative information for interpreting living bodies.
Key terms
- Micro-CT
- A device that uses X-rays to observe fine 3D internal structure without cutting the sample
- Optical coherence tomography (OCT)
- A technology that uses light to observe the cross-sectional structure of tissue without harming the body
- Image reconstruction
- Computing cross-sectional images from projection data taken from many different directions
NewsLab news
Started an open lab for current students
Assistant Professor Okamoto received the Excellent Presentation Award at the Information Photonics Research Meeting 2026
Paper on estimating tissue oxygen saturation published in Biomedical Optics Express
Assistant Professor Okamoto received the Outstanding Reviewer Award from Radiological Physics and Technology
Assistant Professor Okamoto received the AI Optics Outstanding Presentation Award from the AI Optics Research Group of the Optical Society of Japan
ResearchResearch themes
Using micro X-ray CT and optical coherence tomography (OCT) as core technologies, the lab works on medical imaging and image analysis that visualize and quantify the fine structure of biological tissue. It studies the whole process as one continuous flow, from designing imaging devices to optimizing imaging conditions, image reconstruction, and image analysis.
*Illustrative imageMeasuring internal shape with micro-CT
Micro-CT is an X-ray imaging technology that can observe fine internal 3D structure without cutting the sample. Taking into account the trade-offs among resolution, contrast, radiation dose, and imaging time, the lab studies everything from the device to image analysis as one continuous process. It aims for technology that is more precise at lower radiation doses.
*Illustrative imageReading tissue and blood vessels with OCT
OCT uses light to noninvasively observe the cross-sectional structure of tissue, and is widely used in ophthalmology. To extract numerical information on tissue structure and blood vessels from OCT images, the lab aims to build the foundations for 3D structural analysis, quantitative evaluation of vascular networks, and automated analysis with AI.
MembersFaculty
- Assistant ProfessorTakayuki Okamoto
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “X-ray Computed Tomography of Astromaterials -- jsc2024e076997” NASA Johnson Space Center / ROBERT MARKOWITZ NASA-JSC / Public domain (cropped)
- Measuring internal shape with micro-CT: “Computed Tomography (CT) Scan Facility in Navi Mumbai” Goleisureintl / CC BY 4.0 (cropped)
- Reading tissue and blood vessels with OCT: “Optical Coherence Tomography of optic nerve and surrounding retina” Bobjgalindo / CC BY-SA 4.0 (cropped)
- Related lab (羽石研究室): “ESA astronaut Sophie Adenot shows off the Optical Coherence Tomography machine (iss074e0433179)” NASA Johnson Space Center / Public domain (cropped)
- Related lab (野村研究室): “US Navy 051128-N-2115M-047 Hospital Corpsman 2nd Class Stephanie Regalado assigned to the David R. Ray Health Center's Radiology department looks over a x-ray” U.S. Navy photo by Photographer's Mate 2nd Class Shaun McWhinney / Public domain (cropped)
- Related lab (生体イメージング研究室
（菅研究室） ): “An MRI scanner” Walter Davies / CC BY-SA 4.0 (cropped) - Related lab (超
音波グループ 医用生体情報学研究室 （ULBI・平田研究室） ): “Pelvic Ultrasound Examination Navi Mumbai India” Goleisureintl / CC BY 4.0 (cropped)
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