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Natural Products Chemistry Lab
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The lab investigates the target molecules and mechanisms of action of natural bioactive compounds.
AboutAbout the lab
Understanding how living organisms function through natural compounds
The Natural Products Chemistry Lab searches for the target molecules of natural and synthetic bioactive compounds and studies how they work.
Its research also covers phototropism, gravitropism, and allelopathy in plants.
It also lists new pharmaceuticals and functional foods derived from untapped biological resources as research topics.
The lab also examines whether components of seaweeds and plants can inhibit the aggregation of amyloid β.
Key terms
- Bioactive compounds
- Substances that exert some effect on the bodies or cells of living organisms
- Phototropism
- The tendency of plants to change their direction of growth in response to light
- Amyloid β
- A protein fragment. In its papers, the lab studies components that inhibit its aggregation (clumping together)
NewsLab news
Associate Professor Miyamae received the Award for Encouragement of Research in Agricultural Chemistry
Paper published reporting that quercetin promotes the production of hepatocyte growth factor
Paper published in ACS Omega examining the effect of cyanidin derivatives on enzyme aggregation
Paper published reporting Kaemphenolide, a compound from Kaempferia galanga
Paper published in ACS Chemical Biology examining lysosomal damage and its clearance by tetrandrine
ResearchResearch themes
The Natural Products Chemistry Lab studies natural and synthetic bioactive compounds, investigating their target molecules and mechanisms of action. Its research also covers how plants respond to their environment and the functions of semiochemicals that mediate interactions among insects, plants, and animals.
*Illustrative imageTargets and mechanisms of action of bioactive compounds
The lab searches for the molecules (target molecules) that natural and synthetic bioactive compounds act on. It then aims to clarify the mechanisms by which they act.
*Illustrative imagePlant responses to light-induced oxidative stress
The lab studies the mechanisms by which plants use antioxidant activity to respond to oxidative stress caused by light.
*Illustrative imageBiosynthesis and production control of aroma compounds
This research clarifies the biosynthetic pathways by which aroma compounds are produced. The lab also works on controlling their productivity.
*Illustrative imageChemicals that mediate interactions between organisms
The lab investigates the roles of semiochemicals used in interactions among insects, plants, and animals.
MembersFaculty
- ProfessorHideyuki Shigemori
- Associate ProfessorKosumi Yamada
- Associate ProfessorYusaku Miyamae
VoicesStudent voices
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Ecological Trail Garden of Medicinal and Aromatic Plants and South China Medicinal Plants Garden )” LN9267 / CC BY-SA 4.0 (cropped)
- Targets and mechanisms of action of bioactive compounds: “Diselenide TLC chromatogram” Daniel Dróżdż / CC BY 4.0 (cropped)
- Plant responses to light-induced oxidative stress: “Yellow leaves ( )” John Talbot from Ottawa, Canada / CC BY 2.0 (cropped)
- Biosynthesis and production control of aroma compounds: “Lavender field in Misato Town, Akita 20180624e” 掬茶 / CC BY-SA 4.0 (cropped)
- Chemicals that mediate interactions between organisms: “Ladybug preys on aphids” Star61 / CC BY-SA 4.0 (cropped)
- Related lab (Food Resource Utilization Science Lab): “Semi-desert vegetation in Lamu” HassanA2023 / CC BY-SA 4.0 (cropped)
- Related lab (Plant Functional Biochemistry Lab): “Plant Habitat-04 (PH-04) Pepper Seed Planting (KSC-20210408-PH-ILW01 0115)” NASA Kennedy Space Center / NASA/Isaac Watson / Public domain (cropped)
- Related lab (Biological Function Regulation Lab): “Vintage students laboratory (1904), Gdansk University of Technology, Poland” LukaszKatlewa / CC BY-SA 4.0 (cropped)
- Related lab (Insect Semiochemistry Lab): “European honey bee extracts nectar” John Severns (Severnjc) / Public domain (cropped)
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