LAB LOGA page on LabLog, a review site (not the lab's official page)
Molecular Genetics Lab
Machine-translated · View original
A lab that uses mice to explore how gene expression is regulated in mammals.
AboutAbout the lab
Uncovering how genes work, using mice.
The lab studies how genes work in mammals and the mechanisms that regulate them.
Its research targets include how genes respond to hypertensive stimuli, the control of transcription from distant sites, and a phenomenon called genomic imprinting.
The lab creates its own transgenic and knockout mice and analyzes them using methods such as biochemistry, molecular biology, and developmental engineering.
The lab accepts lab visits from undergraduate and graduate students at any time by email.
Key terms
- Genomic imprinting
- A pattern of gene expression in which a gene is active only when inherited from the father or only when inherited from the mother. Differences in DNA methylation are thought to underlie it
- DNA methylation
- A chemical mark attached to DNA. Differences in how it is attached in paternal and maternal germ cells are thought to underlie genomic imprinting
- Transgenic mouse
- A mouse into which another gene or a long stretch of DNA has been integrated. The lab creates them on its own and uses them to analyze gene function
NewsLab news
A review article on genomic imprinting research was published in The Journal of Biochemistry
Prof. Ishihara joined the lab as an International Tenure-Track Assistant Professor
A paper by Professor Tanimoto and colleagues was published in The Journal of Biochemistry
A paper by Professor Tanimoto and colleagues was published in Epigenetics & Chromatin
ResearchResearch themes
Aiming to clarify what kind of activity genome base sequences have in living organisms, the lab studies the regulation of gene expression. It investigates gene function by combining experiments with cultured cells such as ES cells and experiments with mice using transgenic mice, knockout mice, and genome editing.
*Illustrative imageMechanisms of genomic imprinting
Using transgenic mice carrying a yeast artificial chromosome, the lab showed that differences in DNA methylation can be established even after fertilization. It is now searching for epigenetic marks other than the methylation inherited from the parents, and identifying proteins involved in imprinting.
*Illustrative imageHypertension and the regulation of gene expression
Transgenic mice carrying the human renin and human angiotensinogen genes develop hypertension (the Tsukuba hypertensive mouse). Using mice into which a bacterial artificial chromosome has been introduced, as well as knockout mice, the lab investigates how the blood pressure environment regulates the expression of the renin gene.
MembersFaculty
The lab's members consist of faculty, doctoral students, and undergraduate students.As of 2026
- ProfessorKeiji Tanimoto
- Associate ProfessorHitomi Matsuzaki
- Assistant ProfessorTeruhito Ishihara
VoicesStudent voices
Ratings and reviews reflect the experiences of individual current or former students, not the lab's official views. Whether a lab has reviews, or how many, says nothing about the lab itself.
Students who take part in an interview may receive a thank-you gift worth ¥1,000, regardless of what they say.
Student ratings (0 students)
--
--
--
--
--
--
Student voices answer questions like these
- What's great about this lab?
- What did you learn after joining?
- What's the vibe, and what is the professor like?
- Who is this lab for?
- Where do graduates go?
Your experience can help younger students choose their lab. Your name won't be shown.
Write a lab reviewAnonymous · Your draft is saved if you stopRelatedLabs similar to Molecular Genetics Lab
Niwa LabSchool of Life and Environmental Sciences, College of Biological Sciences[Ryusuke Niwa] Specialty: physiological genetics. Neural, ho…
Molecular Neurobiology LabSchool of Life and Environmental Sciences, College of Biological Sciences[Fuminori Tsuruta] Specialty: molecular neurobiology. Resear…
Nakada-Ishikawa LabSchool of Life and Environmental Sciences, College of Biological Sciences[Kazuto Nakada] Specialty: cell biology. Functional morpholo…
Molecular Genetics LabSchool of Life and Environmental Sciences, College of Biological Sciences[Shuichi Kuwayama] Specialty: molecular genetics. Analysis o…The information on this page is compiled by the LabLog team from the lab's public information and interviews. For corrections or removal requests, please contact LabLog, not the lab.
Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Yeast cultures in incubator-1” Masur / CC BY-SA 4.0 (cropped)
- Mechanisms of genomic imprinting: “DNA methylation” Christoph Bock, Max Planck Institute for Informatics / CC BY-SA 3.0 (cropped)
- Hypertension and the regulation of gene expression: “Blood pressure monitoring” rawpixel.com / CC0 (cropped)
- Related lab (Niwa Lab): “Fruit fly (Diptera, Tephritidae) ( )” Insects Unlocked / CC0 (cropped)
- Related lab (Molecular Neurobiology Lab): “All that glitters in the brain” BrainsRusDC / CC BY 4.0 (cropped)
- Related lab (Nakada-Ishikawa Lab): “Leica DM2500 with fluorescence filter cubes” Dietzel65 / CC0 (cropped)
- Related lab (Molecular Genetics Lab): “Dictyostelium discoideum 06” Usman Bashir / CC BY-SA 4.0 (cropped)
About LabLog
LabLog is a lab review app for students only. Student members at each university interview students in labs and publish what they say. Student voices can only be read by students who sign up with a university email address. Operated by bestiee Inc.
Learn more about LabLog ↗Search engines and AI may reference the basic lab info and rating summaries on this page and the description of LabLog. Student voices are for student members only. Automated collection by programs (scraping, or input to or training of AI) is prohibited under Article 8 of the Terms of Service. If you need data for research or analysis, please contact us.