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Microbial Breeding Engineering Lab [College of Biological Sciences]
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A lab that elucidates microbial enzymes and breeds microorganisms with new functions.
AboutAbout the lab
Exploring the power of microbes through their enzymes.
The Microbial Breeding Engineering Lab explores new life phenomena and latent capabilities of microorganisms, and investigates the structure and function of the enzymes involved at the molecular level.
Based on these findings, the lab breeds microorganisms with new functions and also works on applications in biotechnology and the production of useful substances.
The lab has elucidated unique natural metabolic and catalytic mechanisms at the level of enzymes and genes, and has discovered and identified new enzymes.
Students from the College of Biological Sciences and the College of Agro-Biological Resource Sciences can request to do their graduation research here, and the lab also accepts students advancing to graduate school.
Key terms
- Enzyme
- A protein that promotes a specific chemical reaction inside the bodies of living organisms or inside microorganisms
- Breeding
- Obtaining a new variety or strain by selecting or creating organisms with desired traits
- EC number
- A number assigned to an enzyme that the Enzyme Commission of the International Union of Biochemistry and Molecular Biology has recognized as a new enzyme
NewsLab news
Paper published on a microbial enzyme that degrades piperine
Paper published on a microorganism and enzyme that degrade puerarin
Prof. Kobayashi received the Medal with Purple Ribbon in the autumn 2024 Honors
Paper on a curcumin-metabolizing enzyme published in the Journal of Biological Chemistry
ResearchResearch themes
The lab conducts basic research that explores new life phenomena and diverse latent capabilities of microorganisms, and elucidates the structure and function of the related proteins and enzymes at the molecular level. Based on the findings of this basic research, the lab develops and breeds microorganisms with new functions, and also works on biotechnological applications and the production of useful substances.
*Illustrative imageElucidating natural metabolic and catalytic mechanisms
The lab has elucidated unique natural metabolic and catalytic mechanisms at the level of enzymes and genes, and has discovered and identified novel enzymes. Some of these enzymes have been recognized by the Enzyme Commission and assigned new EC numbers.
*Illustrative imageA third type of biocatalyst and hemoglobin
Beyond enzymes derived from microorganisms, the lab has also studied and published work on the discovery of a third type of biocatalyst and on new catalytic activities of hemoglobin.
MembersFaculty
The members of the Microbial Breeding Engineering Lab consist of faculty, postdocs, graduate students, and undergraduate students.As of 2025
- ProfessorMichihiko Kobayashi
- Associate ProfessorYoshiteru Hashimoto
- Assistant ProfessorTakuto Kumano
VoicesStudent voices
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Fermentation tanks in Forty Creek” Gogerr / CC BY-SA 4.0 (cropped)
- Elucidating natural metabolic and catalytic mechanisms: “Microbial culture flasks-set” Lilly_M / CC BY-SA 3.0 (cropped)
- A third type of biocatalyst and hemoglobin: “Pencil cell or Pencil shaped RBC” Ajay Kumar Chaurasiya / CC BY-SA 4.0 (cropped)
- Related lab (Photosynthetic Metabolism Regulation Lab): “Red Algae Haematococcus pluvialis 1000X” Rendodge / CC BY 4.0 (cropped)
- Related lab (Plant Taxonomy, Phylogeny, and Evolution Lab): “Algae under microscope” Gulnazakh / CC BY-SA 4.0 (cropped)
- Related lab (Genome Microbiology Lab): “Enterobacteria phage T2 transmission electron micrograph” SnaxMikn / CC BY-SA 4.0 (cropped)
- Related lab (Nakada-Ishikawa Lab): “Leica DM2500 with fluorescence filter cubes” Dietzel65 / CC0 (cropped)
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