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Tani Lab
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A lab that explores the design principles of living systems through structural biology.
AboutAbout the lab
Exploring the design principles of life through structure
The Tani Lab studies photosynthetic complexes, membrane proteins, and microbial environmental response systems through structural biology.
The lab aims to understand the design principles and network-formation principles of the molecular systems that life has acquired over the course of evolution.
It takes on the question: "Why is life so diverse, yet built on shared principles?"
By understanding the design principles common to living systems, the lab hopes to contribute to new developments in life science.
Key terms
- Structural biology
- A research field that clarifies the three-dimensional structures of biomolecules in order to understand how they function and how they are built.
- LH1-RC
- The light-energy harvesting and conversion system of photosynthetic bacteria. The lab studies its structural diversity and evolutionary principles.
- Quinone
- A molecule that serves as an electron carrier (a molecule that transports electrons) responsible for electron transfer in biological membranes.
ResearchResearch themes
Using the methods of structural biology, the lab investigates the design principles of living systems, focusing on photosynthetic complexes, membrane proteins, and microbial environmental response systems. It aims to find design principles shared across diverse biological phenomena and to understand living systems in an integrated way.
*Illustrative imageStructural Diversity of Light-Harvesting and Electron-Transfer Complexes
The lab analyzes the structures of LH1-RC and LH2 complexes from a variety of photosynthetic bacteria to clarify the evolution of light-energy conversion mechanisms. This is joint research with Prof. Otomo of Ibaraki University, Prof. Kimura of Kobe University, and others.
*Illustrative imagePrinciples of Electron Carrier Flow Network Formation
The lab studies how quinone molecules, which carry out electron transfer, move within biological membranes and what kind of flow networks they form to transfer electrons efficiently. This is joint research with Prof. Otomo, Prof. Kimura, and others.
*Illustrative imageDrawing an Evolutionary Map of Photosynthetic Systems
By integrating three-dimensional structural information with phylogenetic information based on amino acid sequences, the lab aims to draw an "evolutionary map" that gives an overview of how photosynthetic systems have diversified. This is joint research with Prof. Otomo, Prof. Kimura, and others.
*Illustrative imageStructural and Functional Diversity of Environment-Responsive Enzymes
Focusing on alcohol oxidase isozymes, the lab investigates how enzyme function changes in response to environmental change, and aims to clarify the molecular mechanisms and evolutionary background. This is joint research with Prof. Nakagawa of Gifu University and others.
MembersFaculty
- ProfessorKazutoshi Tani
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Crystal structure of chicken brain-type creatine kinase” Cytochrome c at English Wikipedia / CC BY-SA 3.0 (cropped)
- Structural Diversity of Light-Harvesting and Electron-Transfer Complexes: “LH2 top” aegon / CC BY-SA 3.0 (cropped)
- Principles of Electron Carrier Flow Network Formation: “Membrane Protein Structure” Connectivid-D / CC BY-SA 4.0 (cropped)
- Drawing an Evolutionary Map of Photosynthetic Systems: “Protein Crystal Growth Porcine Elastase” 作者不詳 / Public domain (cropped)
- Structural and Functional Diversity of Environment-Responsive Enzymes: “The formation of acetic acid from ethanol by Acetobacter” Wppreen / CC BY-SA 4.0 (cropped)
- Related lab (Animal Systematics / Tsuyuki Lab (Aoi Tsuyuki)): “Yellow papillae flatworm (Thysanozoon nigropapillosum)” Betty Wills / CC BY-SA 4.0 (cropped)
- Related lab (Structural Biology Lab): “Using X-ray diffractometer to solve the 3D structure of membrane proteins of the flagellar system ( )” OIST from Onna Village, Japan / CC BY 2.0 (cropped)
- Related lab (Plant Molecular Biology Lab): “Watering small tomato plants in a greenhouse” Shixart1985 / CC BY 2.0 (cropped)
- Related lab (Microbiology Lab): “Microscope view of bacteria colonies” Korinna / CC BY 4.0 (cropped)
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