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Funamoto Lab
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A lab that recreates the environment inside the body on chips to uncover how cells and blood flow work.
AboutAbout the lab
Exploring living bodies and cells on a foundation of fluid engineering
The Funamoto Lab pursues interdisciplinary research that builds on fluid engineering and integrates biomedical engineering and cell biology.
The lab develops biomimetic chips, which are microfluidic devices that recreate the microenvironment inside the body outside the body.
The lab also works on measurement-integrated blood flow simulation, which combines medical measurement with numerical analysis.
The lab investigates how cells respond in the body's environment, which changes over time and space, and how cells influence each other and the surrounding tissue.
Key terms
- Microfluidic device
- A small chip with microscopic channels. It is used to recreate the microenvironment inside the body outside the body
- Cell migration
- The movement of cells on their own from one place to another
- Hemodynamics
- The field that deals with blood flow and the forces it exerts on blood vessels
- Measurement-integrated simulation
- A method that incorporates actually measured data into computation, combining measurement and calculation to reproduce a phenomenon
NewsLab news
A master's student received the Original Research Student Award from the Tohoku Branch of the Japan Society of Mechanical Engineers
A doctoral student received the Bio-Frontier Outstanding Presentation Award for Young Researchers from the Japan Society of Mechanical Engineers
A doctoral student received the Outstanding Poster Award at the Bioengineering Conference of the Japan Society of Mechanical Engineers
A doctoral student received the Original Research Student Award from the Tohoku Branch of the Japan Society of Mechanical Engineers
A doctoral student received the Best Presentation Award for Young Researcher at ICFD2024
ResearchResearch themes
To advance technologies for treating and preventing disease, it is necessary to clarify the mechanisms that maintain the body's condition and the phenomena inside the body when disease arises and progresses. The lab conducts research that builds on fluid engineering and integrates biomedical engineering and cell biology.
*Illustrative imageChips that recreate the environment inside the body
Cells sense and respond to mechanical stimuli such as blood flow and to chemical stimuli. The lab is developing the "3-in-1 biomimetic chip," which controls three factors (oxygen partial pressure, mechanical stimulation, and chemical stimulation) to recreate the environments of both health and disease.
*Illustrative imageCellular response to hypoxia
Inside cancer tissue, oxygen concentration is uneven and changes over time. Because these changes promote cancer cell migration and the formation of new blood vessels, the lab clarifies how cell movement and properties change with oxygen concentration, and studies how to control them.
*Illustrative imageHemodynamic analysis integrating measurement and computation
Medical devices alone cannot fully measure blood flow inside the body, and computation alone cannot determine accurate conditions, so complete reproduction is difficult. The lab aims to uncover complex blood flow through measurement-integrated simulation, which unifies measurement and computation.
MembersFaculty
The members of the Funamoto Lab consist of faculty, technical staff and technical assistants, and doctoral, master's, and undergraduate students.As of 2026
- ProfessorKenichi Funamoto
VoicesStudent voices
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Microfluidic Reservoir” Kimbalm / CC BY-SA 4.0 (cropped)
- Chips that recreate the environment inside the body: “Microfluidic chip for point-of-care medical devices” FMNLab / CC BY 4.0 (cropped)
- Cellular response to hypoxia: “Clear cell renal cell carcinoma -- high mag” Nephron / CC BY-SA 3.0 (cropped)
- Hemodynamic analysis integrating measurement and computation: “Vel-Streamline-FC” Atif Masood (FetchCFD) / CC BY 4.0 (cropped)
- Related lab (Haga-Tsuruoka Lab): “How ST designs and manufactures semiconductor devices - screenshot 1” STMicroelectronics (original work) Una tantum (screenshot) / CC BY 3.0 (cropped)
- Related lab (Yakeno Lab): “JAXA 1.27m Hypersonic Wind Tunnel P4223597” Kestrel / CC BY-SA 4.0 (cropped)
- Related lab (Ogawa-Saito-He Lab): “Gas Turbine Blade” Pro-Per Energy Services / CC BY-SA 4.0 (cropped)
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