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Nishizawa-Tottori-Osaki Lab
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A lab for soft, wet medical devices made with cells and gels.
AboutAbout the lab
Soft, wet devices for the body.
The Nishizawa Lab develops devices that combine biological components such as cells and proteins with soft, wet materials.
Its main pillars are biofuel cells and sensors, cell and tissue chips, hydrogel electrodes, skin iontronics, and biodelivery.
Based on mechanical engineering and materials science, it is an experimental lab that tackles bio and medical topics in collaboration with Tohoku University Hospital.
No prior knowledge is required, and lab visits are accepted at any time.
Key terms
- Hydrogel
- A soft, jelly-like material swollen with plenty of water
- Iontronics
- Technology that controls signals and substances using the movement of ions instead of electrons. It is highly compatible with living bodies
- Microneedle
- An array of needles so thin that they cause little pain. They can deliver drugs through the skin
NewsLab news
Announced “Oral BIPP,” an in-mouth biofuel cell combined with a mouthpiece
Professor Nishizawa received the Distinguished Achievement Award of the 58th Ichimura Prize in Science
Founded bionto Inc., a startup in biological iontronics technology
Published a review of porous microneedles in Current Opinion in Biomedical Engineering
Announced the dual needle pump, which delivers drugs from both the anode and the cathode
ResearchResearch themes
The lab develops soft and wet devices that combine biological components such as cells and proteins with soft, wet materials. Based on mechanical engineering and materials science, it works on bio and medical topics in collaboration with Tohoku University Hospital.
*Illustrative imageBiofuel Cells and Sensors
Using enzymes, the lab has developed tiny sensors that generate power from fruit juice or body fluids and light up, as well as soft biofuel patches that can be stuck on or wrapped around things. It also announced “Oral BIPP,” an in-mouth biofuel cell that is combined with a mouthpiece and used for oral care.
*Illustrative imageCell and Tissue Chips
The lab works on cell lithography, which attaches cells to targeted locations; cell chips aimed at tests that can replace animal experiments; and research on controlling communication between cells to lead to new medical treatments.
*Illustrative imageHydrogel Electrodes
The lab develops electrodes made of soft hydrogels that contain a lot of water. Together with the School of Medicine, it developed a gel electrode that wraps around nerves, and it is also working on delivering drugs and other substances at targeted times and places using the electroosmotic flow generated by combining anionic and cationic hydrogels.
*Illustrative imageSkin Iontronics
The lab uses porous microneedles as salt bridges that cross the skin. It has announced the “microneedle pump,” an injection-like patch, and the dual needle pump, which places negatively and positively charged needles on the anode and cathode to deliver drugs from both electrodes.
MembersFaculty
The members of the Nishizawa Lab are faculty, doctoral, master's, and undergraduate students, research fellows, and technical assistants.As of 2026
- ProfessorMatsuhiko Nishizawa
- Assistant ProfessorSoichiro Tottori
- Assistant ProfessorShuto Osaki
VoicesStudent voices
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Superabsorber Hydrogel KSG 2917 pK” Petra Klawikowski / CC BY-SA 3.0 (cropped)
- Biofuel Cells and Sensors: “Hard splint mouthguard ( )” Lee Haywood from Wollaton, Nottingham, England / CC BY-SA 2.0 (cropped)
- Cell and Tissue Chips: “Lab on a Chip ( )” National Institute of Standards and Technology / Public domain (cropped)
- Hydrogel Electrodes: “More windows” Jin from Melbourne, Australia / CC BY 2.0 (cropped)
- Skin Iontronics: “Plåster - Adhesive bandage - 2025” Foto: Jonn Leffmann / CC BY 4.0 (cropped)
- Related lab (Haga-Tsuruoka Lab): “How ST designs and manufactures semiconductor devices - screenshot 1” STMicroelectronics (original work) Una tantum (screenshot) / CC BY 3.0 (cropped)
- Related lab (Amezawa-Kawai Lab): “Pila ossido solido SOFC” Asia Vedovi / CC BY 4.0 (cropped)
- Related lab (Kimura Lab): “Lithium-Ionen-Accumulator” Claus Ableiter / CC BY-SA 4.0 (cropped)
- Related lab (Biwa Lab): “Flame-tube-resonance-overlay” MikeRun / CC BY-SA 4.0 (cropped)
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