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Molecular and Cellular Dynamics Measurement Lab
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The lab investigates, at the cellular and molecular level, how cancer cells resist radiation therapy.
AboutAbout the lab
Uncovering how cancer resists treatment
The Molecular and Cellular Dynamics Measurement Lab conducts molecular biology research for cancer treatment with radiation.
Radiation therapy is one of the three major cancer treatments, but much remains unknown about how irradiation affects tumors and the surrounding normal tissue.
The lab studies cell death caused by treatment stress, the mechanisms by which cancer cells suppress it, and the process by which tumor properties change as a result.
Key terms
- Invasion
- Cancer cells spreading into surrounding tissue as if seeping into it.
- Treatment resistance
- When cancer cells become resistant to radiation or drugs, making treatment less effective.
- Extracellular microenvironment
- The immediate environment surrounding cells, including neighboring cells and the protein meshwork outside the cells.
- Synthetic biology
- A research approach that combines parts such as genes to give cells new functions.
ResearchResearch themes
The lab studies cell death caused by stress from treatments such as radiation and by environmental stress that cancer cells themselves create, and the mechanisms by which cancer cells suppress it. It uses experimental methods from biochemistry, molecular biology, cell biology, and synthetic biology.
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MembersFaculty
- Associate ProfessorYasuhito Onodera
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images.
- Top image: “Clonogenic Assay” Jayvadan Vaishnav / CC BY 4.0 (cropped)
- Treatment Stress and Changes in Cancer Properties: “3D cell invasion assay” Kavmic / CC BY 4.0 (cropped)
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