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Radiation Medical Physics Lab
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The lab improves proton therapy with science and engineering technologies.

AboutAbout the lab
Bringing science and engineering technology to the cancer treatment setting.
The lab studies how to apply science and engineering technologies, such as radiation physics, quantum beam application engineering, and imaging engineering, to actual medical care.
Particle therapy, which uses accelerators for medicine, is expected to concentrate the dose on the cancer and reduce the burden on patients' bodies.
Working in collaboration with the Proton Beam Therapy Center at Hokkaido University Hospital, the lab trains medical physics researchers and engineers involved in developing medical devices.
The faculty members in charge belong to the Faculty of Engineering and Hokkaido University Hospital.
Key terms
- Particle therapy
- Radiation therapy that accelerates particles such as protons and directs them at the tumor. It makes it easier to concentrate the dose on the cancer.
- CBCT
- Cone-beam CT. A cone-shaped X-ray beam is rotated around the patient to image the inside of the body in three dimensions.
- DVH
- Dose-volume histogram. A graph showing how much dose is delivered to how much of an organ's volume.
ResearchResearch themes
Image-guided technology has made it possible to deliver treatment that takes into account patient motion, changes in tumor shape, and the body's response during treatment. In collaboration with the Proton Beam Therapy Center at Hokkaido University Hospital, the lab comprehensively studies techniques to enhance treatment effect while limiting side effects, from the standpoints of irradiation, imaging, and computation.
*Illustrative imageIrradiation That Reduces Side Effects and Improves Efficacy
The lab works on developing irradiation techniques and equipment, image-guided techniques that closely incorporate patient motion and changes in tumor shape, dose calculation and optimization methods for high-precision treatment, and verification of treatment effect that considers responses down to the cellular level.
*Illustrative imageCBCT Imaging on Proton Therapy Systems
In proton therapy, it is important to align the patient while considering not only the tumor but also the surrounding tissue and body contour. The lab is investigating whether it is feasible to realize CBCT that uses two sets of X-ray imaging devices simultaneously to shorten imaging time, and four-dimensional CBCT that uses the positions of markers inside the body.
*Illustrative imageDVH Prediction for Proton Therapy
The quality of a treatment plan depends on the planner's experience, and judging whether a plan is the best possible is also difficult. If the DVH of the organs to be protected could be predicted for each case, plan quality and efficiency would be expected to improve. The lab is developing a DVH prediction method that accounts for differences in dose distribution depending on beam direction.
MembersFaculty
- Associate ProfessorSeishin Takao
- Assistant ProfessorKohei Yokokawa
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Mibs probeam” Протонка / CC BY-SA 4.0 (cropped)
- Irradiation That Reduces Side Effects and Improves Efficacy: “BraggPeak-en” Д.Ильин: vectorization / CC0 (cropped)
- CBCT Imaging on Proton Therapy Systems: “Cone Beam CT principle” Aron Saar / CC BY-SA 3.0 (cropped)
- DVH Prediction for Proton Therapy: “DVH” Pabloes / CC BY-SA 4.0 (cropped)
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