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Marine Animal Reproductive Biochemistry Lab (Aquaculture Biology Division)
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The lab studies how fish eggs are formed in order to develop techniques for producing juvenile fish, working in reproductive biochemistry.

AboutAbout the lab
The science of fish eggs.
Under the keyword “the science of fish eggs,” the Marine Animal Reproductive Biochemistry Lab studies how fish eggs are formed (oogenesis).
Building on this basic research, the lab develops seed production techniques for producing juvenile fish for aquaculture, and runs breeding trials using advanced technologies.
The lab is also developing efficient methods for surveying fish resources and biotechnologies that use fish.
Its goal is to clarify the reproductive mechanisms of each species, bring them under human control, and connect this to industries such as aquaculture.
Key terms
- Seed production
- Producing juvenile fish by human hands for use in aquaculture. It is essential for aquaculture that does not depend on wild juveniles.
- Oogenesis
- The process in the ovary by which the cells that give rise to eggs grow, accumulate yolk, and become eggs.
- Vitellogenin
- The precursor of yolk proteins. It is produced in the liver under the action of female sex hormones and carried by the blood to the eggs.
ResearchResearch themes
As wild fishery resources decline and demand for seafood grows, efficient and sustainable aquaculture and stock enhancement technologies are needed. Based on basic physiological research on oogenesis in fish, the lab works on developing seed production and breeding techniques.
*Illustrative imageDeveloping seed production techniques for fish
Many fish do not spawn simply by being kept in a tank. Examples include the Japanese eel and the fox jacopever (Sebastes vulpes), a viviparous fish that takes many years to mature. The lab develops techniques for efficiently producing juveniles of such fish.
*Illustrative imageDistinguishing sex and maturity
It is important to know the sex and the stage of maturity of fish before and after hormone administration. The lab uses estrogen released from ovarian follicle cells, and the oogenesis-related proteins that the liver releases in response to it, as markers for this determination.
*Illustrative imageImmunoassays that measure blood components
The lab develops, for each fish species, methods that measure fish hormones and vitellogenin in blood by using the reaction between antigens and antibodies. In the grey mullet, continued measurement makes it possible to predict the timing of spawning and of hormone administration.
MembersFaculty
At the Marine Animal Reproductive Biochemistry Lab, faculty from the Field Science Center for Northern Biosphere also take part in supervising students.
- ProfessorTakashi Todo
- ProfessorNaoshi Hiramatsu
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Erwin National Fish Hatchery eyed rainbow trout eggs 24 March 2022” Ryan Hagerty/USFWS / Public domain (cropped)
- Developing seed production techniques for fish: “Sebastes schlegelii Muroran” Totti / CC BY-SA 4.0 (cropped)
- Distinguishing sex and maturity: “Sujiko by sor” sor / CC BY 2.0 (cropped)
- Immunoassays that measure blood components: “Bora201312” Izuzuki / CC BY-SA 3.0 (cropped)
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(菅原一輝 助教) ): “CSIRO ScienceImage 952 Undaria pinnatifida Japanese kelp” division, CSIRO / CC BY 3.0 (cropped)
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