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Biological Data Science Lab
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The lab develops data science for healthcare and manufacturing systems from small amounts of data.
AboutAbout the lab
Creating new value from small data.
The Biological Data Science Lab studies methods for building useful AI from small amounts of data (small data).
Rare events and data that are costly to collect cannot be obtained in large quantities.
The lab therefore develops machine learning algorithms and mathematical models that also incorporate the experience and knowledge of experts.
Working across two universities, Hokkaido University and Nara Institute of Science and Technology, the lab applies this research to the development of medical AI, medical devices, and production systems.
Key terms
- Small data
- Data that is limited in number and cannot be collected in large quantities. It arises from rare phenomena or from costly measurements.
- Mathematical model
- A description of how a phenomenon behaves, expressed in mathematical equations. It serves as the basis for analysis, control, and prediction.
- Autonomic nervous system
- The nervous system mechanism that regulates the internal organs, blood flow, body temperature, and more independently of consciousness.
NewsLab news
A paper by visiting researchers and colleagues analyzing factors in the postoperative course of elderly patients has been accepted by Anesthesia & Analgesia
A patent on epileptic seizure prediction has been granted in the US
Results from the CREST project "Super Sensing of Dogs" have been published in Frontiers in Veterinary Science
ResearchResearch themes
Deliberately focusing on small data, the lab aims to create value that big data cannot provide, through analysis that also incorporates people's experience and tacit knowledge. It focuses on medical AI that draws on biosignal processing and on digital transformation (DX) systems that raise productivity in manufacturing.
*Illustrative imageMachine Learning
Data from biosignals, omics, and production systems are hard to collect in sufficient quantity, so approaches different from those used for big data are needed. The lab develops algorithms for time series, anomaly detection, imbalanced data, causal inference, and more.
*Illustrative imageMathematical Modeling
To understand, analyze, and control a phenomenon, a mathematical model that describes its behavior is needed. Using knowledge from neuroscience, physiology, and physical chemistry, the lab attempts to model phenomena such as the activity of neurons in the brain.
*Illustrative imageAutonomic Nervous Activity
The autonomic nervous system regulates the internal organs, circulation, body temperature, metabolism, and immunity independently of consciousness, and it also interacts with sleep and wakefulness, feeding, stress, and emotion. The lab investigates its functions and their relationship to disease and emotion.
*Illustrative imageSoftware as a Medical Device
Software used to support diagnosis or treatment is called SaMD (Software as a Medical Device). For medical AI that analyzes biosignals, the lab carries out the whole process, from data collection and development to regulatory approval procedures.
MembersFaculty
The members of the Biological Data Science Lab (Hokkaido University) consist of faculty members, doctoral and undergraduate students, researchers, technical staff, and visiting researchers.As of 2026
- ProfessorKoichi Fujiwara
- Assistant ProfessorShota Saeda
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “BRDHH con papel” Bobjgalindo / CC BY-SA 4.0 (cropped)
- Machine Learning: “K Means Example Step 4” Weston.pace / CC BY-SA 3.0 (cropped)
- Mathematical Modeling: “Synapsin and CamK2 positive neurons” ManuelSchottdorf / CC BY-SA 4.0 (cropped)
- Autonomic Nervous Activity: “Chest belt with heart beat registration” Sönke Kraft aka Arnulf zu Linden / CC BY-SA 3.0 (cropped)
- Software as a Medical Device: “EEG electrode” Gspilich2 / CC BY-SA 3.0 (cropped)
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- Related lab (Diversity Biology Ia Lab): “Micrura verrilli” Marlin Harms / CC BY 2.0 (cropped)
- Related lab (Hokkaido University Field Ornithology Lab): “Otus elegans from iNaturalist photo” WeitingLiu (weitingliu) / CC BY 4.0 (cropped)
- Related lab (Diversity Biology Ib Lab): “Drosophila mimica” Shchurch / CC BY-SA 4.0 (cropped)
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