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Yoshida Lab
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The lab explores the functions and production of polyunsaturated fatty acids such as DHA.
AboutAbout the lab
Exploring the functions of DHA at the molecular level.
The Yoshida Lab studies the functions of long-chain polyunsaturated fatty acids (LC-PUFAs) such as DHA and EPA.
Because LC-PUFAs have many double bonds, they tend to take a bent shape and are thought to play a role in maintaining the fluidity of cell membranes.
The lab aims to discover physiological functions that are not yet known and to clarify their mechanisms at the molecular level.
It also carries out practical research on getting microorganisms to produce LC-PUFAs efficiently.
Key terms
- Polyunsaturated fatty acid (PUFA)
- A fatty acid with multiple double bonds in its carbon chain. DHA and EPA are typical examples, and they have low melting points
- Cell membrane
- The membrane that separates a cell from its surroundings. It controls the passage of substances and also serves as a place for sensing the external environment
- Model organism
- An organism, such as E. coli or yeast, whose characteristics are well understood and which is widely used in experiments
ResearchResearch themes
The lab aims to clarify the roles that long-chain polyunsaturated fatty acids (LC-PUFAs) play inside cells and the molecular mechanisms behind them. Because LC-PUFAs are also important nutrients for humans and animals, the lab also investigates methods for producing them efficiently.
*Illustrative imageFunctions of LC-PUFAs in cells
The lab expresses genes related to LC-PUFAs in model organisms and examines how these fatty acids affect cells.
*Illustrative imageProducing LC-PUFAs with microorganisms
The DHA and EPA found in the sea are produced by certain bacteria, phytoplankton, and seaweed. The lab explores ways to use such microorganisms to produce LC-PUFAs efficiently.
MembersFaculty
- Assistant (Joshu)Kiyohito Yoshida
VoicesStudent voices
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Docosahexaenoic-acid-3D-sf” Ben Mills / Public domain (cropped)
- Functions of LC-PUFAs in cells: “The surface of highly curved lipid bilayer” Semen Yesylevskyy / CC BY 4.0 (cropped)
- Producing LC-PUFAs with microorganisms: “CSIRO ScienceImage 6739 photobioreactor” CSIRO, CSIRO / CC BY 3.0 (cropped)
- Related lab (Hori Lab): “Dense poplar wood seba beach” Quinn Desilets / CC BY-SA 4.0 (cropped)
- Related lab (RTNakano Lab): “-Chlorophytum comosum-02” Wildfeuer / CC BY 2.5 (cropped)
- Related lab (Morphology and Function II Lab): “Arabidopsis thal kz1” Krzysztof Ziarnek, Kenraiz / CC BY-SA 3.0 (cropped)
- Related lab (Tanaka Lab): “Drosophila melanogaster 53362116” Alexis / CC BY 4.0 (cropped)
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