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Organometallic Chemistry Lab
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A lab that designs and develops organic synthesis catalysts that give rise to groundbreaking chemical reactions.

AboutAbout the lab
Creating new catalysts as molecular creators.
The Organometallic Chemistry Lab studies groundbreaking chemical reactions that revolutionize synthetic organic chemistry, and the catalysts that make them possible.
Pharmaceuticals and functional organic materials come out of synthetic organic chemistry.
By combining organic chemistry, coordination chemistry, computer graphics, and quantum chemical calculations, the lab designs molecules with structures and functions that do not yet exist in the world.
It also searches for catalysts in domains beyond single molecules, such as chemically modified solid surfaces and molecular assemblies.
Key terms
- Catalyst
- A substance that makes a chemical reaction proceed more easily, or steers it in a desired direction, without itself being changed
- Chiral
- A property of molecules whose mirror image cannot be superimposed on the original, like a right hand and a left hand
- Quantum chemical calculation
- A method that calculates the behavior of electrons using the equations of quantum mechanics to predict molecular properties and reaction pathways
NewsLab news
A doctoral student received an Outstanding Enrei Award at the Akai Ito Kai
Students received an Oral Presentation Award and a Poster Award at the Symposium on Organometallic Chemistry
A paper on the dichlorination of alkenes was accepted by Synlett
A paper on the synthesis of polycyclic pyrrolidines was accepted by Chemical Science
A paper on the reaction mechanism of the gold-catalyzed asymmetric aldol reaction was accepted by ACS Catalysis
ResearchResearch themes
The lab discovers groundbreaking chemical reactions that revolutionize synthetic organic chemistry, and designs and develops the catalysts that make them possible. By combining organic chemistry and coordination chemistry with quantum chemical calculations and computer graphics, it creates molecules with new structures and new functions.
*Illustrative imageDirectly remodeling carbon–hydrogen bonds
If the carbon–hydrogen bonds found everywhere in organic molecules can be converted into other bonds at targeted positions, complex compounds can be obtained in few steps. Focusing on weak interactions between a catalyst and a substrate, the lab develops asymmetric synthesis methods that give only one of two chiral compounds that are mirror images of each other.
*Illustrative imageDeveloping light-driven chemical reactions
Ordinary chemical reactions use heat as their energy source, but this lab takes on reactions powered by light. Light can supply energy larger than heat by orders of magnitude, which makes possible reactions that were previously considered impossible. The lab controls the behavior of the extremely highly reactive species generated by light through the combination of molecular design and metal catalysts.
*Illustrative imageDesigning catalysts with quantum chemical calculations
The lab uses quantum chemical calculations to clarify how a catalyst works, and applies those findings to the design of the next catalyst. It also incorporates the AFIR method developed by Prof. Maeda of the Theoretical Chemistry Lab, creating asymmetric synthesis catalysts guided by computation.
MembersFaculty
The members of the Organometallic Chemistry Lab are faculty, secretaries, and students in the doctoral, master's, and undergraduate programs.As of 2026
- Associate ProfessorYohei Shimizu
- Assistant ProfessorYusuke Masuda
VoicesStudent voices
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Double vac line side view” Polimerek / CC BY-SA 3.0 (cropped)
- Directly remodeling carbon–hydrogen bonds: “(R)-(−)-carvone-from-xtal-3D-balls-A” Ben Mills / Public domain (cropped)
- Developing light-driven chemical reactions: “1.Photocatalysis in oxygen” RainbowDasha / CC BY 4.0 (cropped)
- Designing catalysts with quantum chemical calculations: “Otera's catalyst 3D ball” Jynto (talk) / CC0 (cropped)
- Related lab (Inorganic Chemistry Lab): “Lithium-Ion Cell cylindric” RudolfSimon / CC BY-SA 3.0 (cropped)
- Related lab (Organic Chemistry II Lab): “Column chromatography spinach” Kostasmes95 / CC BY 4.0 (cropped)
- Related lab (Organic Chemistry I Lab): “Chemical solutions” Bismoldirs / CC BY-SA 4.0 (cropped)
- Related lab (Theoretical Chemistry Lab): “Potential Energy Surface for Water” AimNature / CC BY-SA 3.0 (cropped)
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