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Quantum Beam Applied Medical Engineering Lab
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The lab applies quantum beams to medicine to make proton beam cancer therapy more accurate.
AboutAbout the lab
Next-generation diagnosis and treatment through collaboration between medicine and engineering.
The Quantum Beam Applied Medical Engineering Lab studies how to use quantum beams and radiation in medicine.
In cooperation with the Proton Beam Therapy Center and the Department of Medical Physics at Hokkaido University Hospital, the lab aims to realize next-generation diagnosis and treatment.
The lab also actively pursues joint research with companies and advances technology development through industry-academia collaboration.
The lab is run in close cooperation with the Radiological Medical Physics field of the Graduate School of Biomedical Science and Engineering, and graduate students from the Graduate School of Engineering and the Graduate School of Biomedical Science and Engineering work together with fourth-year undergraduates of the Faculty of Engineering.
Key terms
- Proton beam therapy
- Radiation therapy in which hydrogen nuclei (protons) are accelerated and directed at a cancer. The beam stops at a specific depth inside the body.
- X-ray fluoroscopic image
- An image that shows the inside of the body like a video by continuously irradiating it with X-rays.
- Pressure shock wave
- A wave generated inside the body when it is hit by a proton beam, which propagates as a sudden change in pressure.
NewsLab news
A master's student received the Bronze Prize of the Student Encouragement Award from the Japan Society of Medical Physics
A paper by doctoral students and others was accepted by the Journal of Applied Clinical Medical Physics
A master's student received the Silver Prize of the Student Encouragement Award from the Japan Society of Medical Physics
A master's student received a Certificate of Merit Award at the 5th International Conference on Radiological Physics and Technology
ResearchResearch themes
In cooperation with Hokkaido University Hospital, the lab advances research on applying quantum beams and radiation to medicine. Its work includes imaging technology for accurately targeting cancers that move with breathing, technology for verifying where a proton beam has landed, and dose analysis that takes biological effects into account.
*Illustrative imageViewing moving tumors in real time
When a tumor inside the body moves with breathing, it becomes difficult to irradiate accurately, including the surrounding organs. The lab studies a method that models internal body deformation from internal markers at the time of treatment planning and from body surface information, and synthesizes three-dimensional images of the tumor and surrounding organs in real time.
*Illustrative imageFinding markers with AI
In real-time tumor-tracking radiotherapy, the position of metal markers placed near the tumor is recognized from X-ray fluoroscopic images. The lab studies a deep learning method that can identify markers even when their shape changes, and a method for synthesizing training images from digital data of the human body.
*Illustrative imageLocating where the proton beam lands using sound
There is a non-negligible uncertainty in where in the body a proton beam has landed. Together with Bogazici University (Türkiye) and Kyoto University, the lab develops technology that captures in real time the pressure shock waves generated during irradiation to reduce uncertainty in the irradiation position.
*Illustrative imageDose that takes biological effects into account
The effect of proton beam therapy depends not only on the physical dose but also on factors such as the recovery capacity of cells. Together with the Faculty of Medicine and the Faculty of Veterinary Medicine, the lab conducts irradiation experiments on cancer cells and builds biophysical models that incorporate these factors simultaneously.
MembersFaculty
The members of the Quantum Beam Applied Medical Engineering Lab consist of faculty and students in the doctoral program, master's program, and undergraduate program.As of 2026
- ProfessorTaeko Matsuura
- Associate ProfessorNaoki Miyamoto
- Associate ProfessorSeishin Takao
- Assistant ProfessorChen Chen
- Assistant ProfessorKohei Yokokawa
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Cyclotron - University of Washington” Ikiwaner / CC BY-SA 3.0 (cropped)
- Viewing moving tumors in real time: “Lung-Window(L-600)(W1600)Axial” יוסי רן / CC BY-SA 4.0 (cropped)
- Finding markers with AI: “Percutaneous vertebroplasty, L2-L4, fluoroscopy prior, case 01” Jmarchn / CC BY 4.0 (cropped)
- Locating where the proton beam lands using sound: “HIFU Transducers Compared with Cardiac Imaging Probe” Chris Adams / CC BY-SA 4.0 (cropped)
- Dose that takes biological effects into account: “HeLa-I” National Institutes of Health (NIH) / Public domain (cropped)
- Related lab (Nuclear Reactor Engineering Lab): “Cerenkov Effect” United States Nuclear Regulatory Commission / Public domain (cropped)
- Related lab (Quantum Beam Materials Analysis and Harsh-Environment Semiconductor Device Engineering Lab): “Syn diamonds” 2x910 / CC BY-SA 4.0 (cropped)
- Related lab (Micro Biomechanics Lab): “Fibroblastid” Heiti Paves / CC BY-SA 3.0 (cropped)
- Related lab (Nuclear Environmental Materials Lab): “Onkalo driving tunnel” kallerna / CC BY-SA 4.0 (cropped)
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