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Reactive Organic Chemistry Lab
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The lab designs and synthesizes organic molecules that no one has made before.
AboutAbout the lab
Making new molecules to surprise the world.
The Reactive Organic Chemistry Lab synthesizes organic molecules that no one has ever made before and studies their structures and functions.
The lab is divided into the Structural Organic Chemistry Team and the Electrolysis Team, and covers everything from molecular design and synthesis to reactions driven by electricity.
From molecules it calls “carbonyl strings,” the lab has produced dyes and small-ring porphyrins.
The lab also pursues research that brings machine learning into organic chemistry, and takes part in research applying polyketones to batteries and cancer medicine.
Key terms
- Porphyrin
- A compound in which four pyrroles form a ring. This skeleton is shared by heme and chlorophyll, and porphyrins are often called the pigments of life.
- Organic electrosynthesis
- A method of causing reactions of organic molecules by passing an electric current. Electricity is used in place of oxidizing or reducing agents.
- Fluorescent dye
- A molecule that absorbs light and emits light of a different color. It is used for cell staining and molecular sensors.
NewsLab news
A student received the TCI Student Poster Award at the 36th Symposium on Basic Organic Chemistry
A paper on a macrocyclic BODIPY that withstands superacid was published in Nature Communications
A student received the Student Presentation Award at the Spring Annual Meeting of the Chemical Society of Japan
A student received the Best Presentation Award at an international conference on materials science
A student received the TCI Student Poster Award at the 35th Symposium on Basic Organic Chemistry
ResearchResearch themes
The lab creates new molecules through organic synthesis and studies their shapes and functions. The Structural Organic Chemistry Team works on acid-resistant dyes and small-ring porphyrins, and the Electrolysis Team works on organic synthesis using electricity.
*Illustrative imageA Dye That Still Glows in Superacid
The fluorescent dye BODIPY is sensitive to acid and decomposes, losing its fluorescence, even in dilute hydrochloric acid. By fusing it with a framework that tightly clamps the boron, the lab made a dye that keeps emitting light even in superacid.
*Illustrative imageMerging Machine Learning and Organic Chemistry
The lab turned researchers' “experience and intuition” into data through image-based machine learning, and built a system that predicts the mixing ratio of a solid mixture from a photograph. Reaction yields can also be tracked from photographs.
*Illustrative imageSmall-Ring Porphyrins
The lab synthesized, for the first time in the world, a cyclic molecule made of three pyrroles (calix[3]pyrrole), and clarified why porphyrins cannot be formed from three pyrroles. It is pioneering the chemistry of small-ring porphyrins.
*Illustrative imageOrganic Synthesis Using Electricity
Electrolytic reactions make it possible to carry out efficiently reactions that are difficult with ordinary reagents. The lab is developing electrochemical fixation reactions that incorporate carbon dioxide into organic molecules to make carboxylic acids.
MembersFaculty
The members of the Reactive Organic Chemistry Lab are faculty, researchers, PhD students, master's students, undergraduate students, and administrative assistants.As of 2026
- ProfessorYasuhide Inokuma
- Associate ProfessorHisanori Senboku
- Project Assistant ProfessorYuki Ide
- Project Assistant ProfessorNarendra Nath Pati
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Acetylacetone-keto-tautomer-from-xtal-Mercury-3D-balls” Ben Mills / Public domain (cropped)
- A Dye That Still Glows in Superacid: “Fluorescence of BODIPY derivative” Sunmosk / CC BY 4.0 (cropped)
- Merging Machine Learning and Organic Chemistry: “Salt and pepper macro image in studio” Jon Sullivan / Public domain (cropped)
- Small-Ring Porphyrins: “Porphyrin-3D-balls” Jynto (talk) / CC0 (cropped)
- Organic Synthesis Using Electricity: “Dry-ice-09560” Nevit / CC BY-SA 3.0 (cropped)
- Related lab (Molecular Assembly Chemistry Lab): “Simulated structure of the water hexane interface” Cnrowley / CC BY-SA 4.0 (cropped)
- Related lab (Solid-State Reaction Chemistry Lab): “Crystals growing from melted sulfur” AlexmarPhoto / CC BY 4.0 (cropped)
- Related lab (Polymer Chemistry Lab): “Polyethylene balls5” Lluis tgn / CC BY-SA 3.0 (cropped)
- Related lab (Organoelement Chemistry Lab): “Mortar and Pestles - DPLA - ee6d0252453ce429f24c8d03e3ba32ae” 作者不詳 / Public domain (cropped)
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