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Oishi Lab (Division of Biofunctional Molecular Engineering · National Institute of Advanced Industrial Science and Technology)
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A lab that explores how the circadian clock works and how it relates to disease and diet.
AboutAbout the lab
Thinking about health through the circadian clock
The Oishi Lab studies the circadian clock, a mechanism that keeps rhythm on a cycle of about 24 hours.
The central clock is in the brain, but clock genes work throughout the body, including in the liver and heart.
The lab investigates how the circadian clock relates to sleep disorders and lifestyle-related diseases, focusing on clock genes and approaching the question from molecular mechanisms.
The lab aims to adjust the body's rhythms through lifestyle habits centered on diet, and to apply this to preventing and improving diseases and to chrono-nutrition.
Key terms
- Circadian clock
- A mechanism inside living organisms that keeps rhythm on a cycle of about 24 hours. It creates the rhythms of sleep and metabolism.
- Clock genes
- Genes that generate the rhythm of the circadian clock. The rhythm arises as these genes regulate one another's activity.
- Chrono-nutrition
- A field that studies how not only what you eat but also when you eat affects the body.
ResearchResearch themes
The lab studies, at the molecular level and with a focus on clock genes, how the circadian clock generates its rhythm and how it relates to diseases such as sleep disorders and lifestyle-related diseases. It also aims to actively control the body's rhythms through lifestyle habits centered on diet.
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MembersFaculty
- Visiting ProfessorKatsutaka Oishi
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “From Day Into Night” کریستیانا هاموک ناسا / Public domain (cropped)
- Molecular mechanisms of the circadian clock and disease: “Mouse running on a standard wheel” Manuelito2021consupadre / CC BY-SA 4.0 (cropped)
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