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Sato Lab
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The lab develops technologies to control biological phenomena with light, linking them to medicine and biomanufacturing.
AboutAbout the lab
Controlling biological phenomena with light, exactly as desired
The Sato Lab is developing entirely new foundational technologies for manipulating biological phenomena with light.
Applying these foundational technologies, the lab creates technologies that freely control genome editing, gene expression, and intracellular signaling, both inside cells and in living organisms.
The lab manipulates genes involved in biological phenomena and diseases with light in order to elucidate how they function.
The lab aims to make it possible to treat a variety of diseases, including cancer and genetic disorders, through new light-based approaches.
Key terms
- Genome editing
- A technology that rewrites genetic information at a targeted location in an organism's genome
- Fluorescent protein
- A protein that emits light of a different color when illuminated. Used as a marker for observing biomolecules
- Probe
- A molecule designed to serve as a marker that emits light when it captures a specific biomolecule
NewsLab news
A paper by Assistant Professor Hashimoto and colleagues was published in Antibody Therapeutics
A lab member won the Sekisui Chemical Award at JSEC
A paper on controlling gene manipulation with compounds was published in Communications Biology
A paper by Prof. Sato and colleagues was published in Communications Biology
A paper by Lecturer Kiuchi and colleagues was published in Structure
ResearchResearch themes
The lab develops new foundational technologies for precisely controlling biological phenomena with light. It also designs and develops functional molecules that visualize biomolecules, and with molecular imaging technology at its core, aims to understand biological functions and diseases at the molecular level.
*Illustrative imageControlling biological phenomena with light
By shining light on cells and living organisms, it has become possible to rewrite the genetic information encoded in the genome at specific locations and to selectively activate the function of target genes. In recent years, the lab has also been developing gene regulation technologies that use not only light but also compounds, nucleic acids, and bacteria.
*Illustrative imageMaking biomolecules glow to see them
The lab designs and develops functional molecules (probes) that capture specific biomolecules and emit light, using fluorescent proteins and bioluminescent proteins. It has become possible to see in real time how biomolecules function inside living cells and organisms, including their temporal and spatial dynamics.
MembersFaculty
The Sato Lab's members include faculty, postdoctoral researchers, doctoral, master's, and undergraduate students, technicians, and high school students.As of 2026
- ProfessorMoritoshi SatoPublications ↗
- LecturerTai Kiuchi
- Assistant ProfessorKoji Hashimoto
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Green fluorescent protein (GFP) in Eppendorf Tubes” Juan Carlos Fonseca Mata / CC BY-SA 4.0 (cropped)
- Controlling biological phenomena with light: “Streptococcus pyogenes Cas9-DNA-RNA complex PDB 4OO8” Deposition authors: Nishimasu, H., Ishitani, R., Nureki, O.; Visualization author: Synpath / CC0 (cropped)
- Making biomolecules glow to see them: “Varbuss” Heiti Paves / CC BY-SA 3.0 (cropped)
- Related lab (吉本(敬太郎)研究室): “DNA double helix 45” Jerome Walker,Dennis Myts / Public domain (cropped)
- Related lab (新井研究室): “Myoglobin” AzaToth / Public domain (cropped)
- Related lab (若杉(桂輔)研究室): “Angiogenesis medical animation still” www.scientificanimations.com / CC BY-SA 4.0 (cropped)
- Related lab (豊田(太郎)研究室): “Phosphatidylcholine liposomes at phase-contrast microscopy” ArkhipovSergey / CC BY-SA 4.0 (cropped)
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